Rocastine (AHR-11325) |
| Catalog No.GC30455 |
Rocastine(AHR-11325)은 항히스타민제로 작용하는 선택적 비진정 H1 길항제입니다.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 91833-49-7
Sample solution is provided at 25 µL, 10mM.
;)
,-1-7$$$37316672.jpg');)
;)
;)
$$$36806353.jpg');)
;33(7)%EF%BC%9A546-561$$$37156877.jpg');)
;)
;)
;)
%201124-1138.$$$35908550.jpg');)
%20766-780.$$$37100057.jpg');)
%20418-432.$$$36893736.jpg');)
%EF%BC%9A-240-255.$$$35108512.jpg');)
533-545$$$36543525.jpg');)
%201-13.$$$36600053.jpg');)
;)
Rocastine is a selective, nonsedating H1 antagonist, acting as an antihistamine.
Rocastine is effective with a 15 min pretreatment time (PD50 = 0.13 mg/kg) as it is with a 1 hr pretreatment time (PD50 = 0.12 mg/kg). Rocastine protects guinea pigs from collapse induced by aerosolized antigen; rocastine is approximately 36x more potent than diphenhydramine and as potent as oxatomide and terfenadine. Rocastine does not alter the EEG of cats at doses in vast excess (150x) of its antihistaminic dose nor does it potentiate yohimbine toxicity in mice[1].
[1]. Nolan JC, et al. Rocastine (AHR-11325), a rapid acting, nonsedating antihistamine. Agents Actions. 1989 Aug;28(1-2):53-61.
Average Rating: 5 (Based on Reviews and 33 reference(s) in Google Scholar.)
GLPBIO products are for RESEARCH USE ONLY. Please make sure your review or question is research based.
Required fields are marked with *