Sarilesin (trifluoroacetate salt) |
Catalog No.GC90537 |
AT2 수용체 작용제 펩타이드
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Sample solution is provided at 25 µL, 10mM.
Sarilesin is a peptide angiotensin II type 2 (AT2) receptor agonist.1 It binds to AT2 receptors (Ki = 0.14 nM) and induces neurite outgrowth in NG108-15 cells when used at a concentration at 100 nM, an effect that can be inhibited by the AT2 receptor antagonist PD 123310. Intrathecal administration of sarilesin (1 µg/µl) increases mean arterial pressure and heart rate in rats.2
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