>>Signaling Pathways>> Membrane Transporter/Ion Channel>> Calcium Channel>>Sipatrigine

Sipatrigine (Synonyms: BW 619C89)

Catalog No.GC11041

신경보호제인 시파트리진(619C89)은 중추신경계를 관통하는 글루타메이트 방출 억제제, 전압 의존성 나트륨 채널 및 칼슘 채널 억제제입니다.

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Sipatrigine Chemical Structure

Cas No.: 130800-90-7

Size 가격 재고 수량
10mg
US$302.00
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50mg
US$1,268.00
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Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents Related Products

Sipatrigine, a neuroprotective agent, is a glutamate release inhibitor, voltage-dependent sodium channel and calcium channel inhibitor, penetrating the central nervous system. Has potential to treat focal cerebral ischemia and stroke[1][2].

References:
[1]. Leach MJ, et al. BW619C89, a glutamate release inhibitor, protects against focal cerebral ischemic damage. Stroke. 1993 Jul;24(7):1063-7.
[2]. Atticus H. Hainsworth, et al. Sipatrigine (BW 619C89) is a Neuroprotective Agent and a Sodium Channel and Calcium Channel Inhibitor. CNS Drug Reviews. Vol. 6, No. 2, pp. 111-134.

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Average Rating: 5 ★★★★★ (Based on Reviews and 17 reference(s) in Google Scholar.)

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