Sophocarpine monohydrate |
Catalog No.GC64223 |
소포카르핀(일수화물)은 항바이러스, 항종양, 항염증과 같은 많은 약리학적 특성을 갖는 전통 한약재인 Sophora flavescens에서 추출한 중요한 알칼로이드 중 하나입니다.
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Cas No.: 145572-44-7
Sample solution is provided at 25 µL, 10mM.
Sophocarpine (monohydrate) is one of the significant alkaloid extracted from the traditional herb medicine Sophora flavescens which has many pharmacological properties such as anti-virus, anti-tumor, anti-inflammatory. Sophocarpine (monohydrate) significantly inhibits the growth of gastric cancer (GC) cells through multiple mechanisms such as induction of autophagy, activation of cell apoptosis and down-regulation of cell survival PI3K/AKT signaling pathway. Sophocarpine (monohydrate) has been demonstrated to have anti-tumor activity in various cancer cells, including hepatocellular carcinoma, prostate cancer and colorectal cancer[1].
[1]. Huang Y, et al. Sophocarpine inhibits the growth of gastric cancer cells via autophagy and apoptosis. Front Biosci (Landmark Ed). 2019 Mar 1;24:616-627.
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