Sorivudine |
| Catalog No.GC39552 |
소리부딘(BV-araU)은 경구 활성 합성 피리미딘 뉴클레오사이드 항대사제 약물입니다.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 77181-69-2
Sample solution is provided at 25 µL, 10mM.
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Sorivudine (BV-araU) is an orally active synthetic pyrimidine nucleoside antimetabolite drug. Sorivudine derives its antiviral activity from selective conversion by a specific thymidine kinase present in certain DNA viruses to nucleotides, which can in turn interfere with viral DNA synthesis[1].
[1]. Diasio RB, et al. Sorivudine and 5-fluorouracil; a clinically significant drug-drug interaction due to inhibition of dihydropyrimidine dehydrogenase. Br J Clin Pharmacol. 1998 Jul;46(1):1-4. [2]. Whitley RJ, et al. Sorivudine: a potent inhibitor of varicella zoster virus replication.Adv Exp Med Biol. 1996;394:41-4.
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