Sphingosine-d7 (d18:1) (Synonyms: (-)-Sphingosine-d7, D-erythro-Sphingosine C-18-d7) |
| Catalog No.GC40104 |
스핑고신-d7(d18:1)(에리트로스핑고신-d7)은 D-에리트로-스핑고신으로 표시된 중수소입니다. D-에리트로-스핑고신(Erythrosphingosine)은 EC50이 8 μM인 p32-키나아제의 매우 강력한 활성제이며 단백질 키나아제 C(PKC)를 억제합니다. D-에리트로스핑고신(Erythrosphingosine)은 또한 PP2A 활성화제입니다.
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Cas No.: 1246304-34-6
Sample solution is provided at 25 µL, 10mM.
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Sphingosine-d7 (d18:1) is intended for use as an internal standard for the quantification of sphingosine (d18:1) by GC- or LC-MS. Sphingosine (d18:1) is formed primarily from the breakdown of ceramide. Sphingosine (d18:1) inhibits protein kinase C and phosphatidic acid phosphohydrolase, whereas it activates phospholipase D and diacylglycerol (DAG) kinase. Phosphorylation of sphingosine (d18:1) by sphingosine kinases 1 and 2 (SPHK1, SPHK2) produces sphingosine-1-phosphate, a potent bioactive lipid that exhibits a broad spectrum of biological activities including cell proliferation, survival, migration, cytoskeletal organization, and morphogenesis.
Average Rating: 5 (Based on Reviews and 6 reference(s) in Google Scholar.)
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