Succinyl-Coenzyme A (sodium salt) (Synonyms: Succinyl-CoA) |
| Catalog No.GC44961 |
석시닐-코엔자임 A (Succinyl-CoA) 나트륨은 시트르산 회로의 중간체입니다.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 108347-97-3
Sample solution is provided at 25 µL, 10mM.
;)
,-1-7$$$37316672.jpg');)
;)
;)
$$$36806353.jpg');)
;33(7)%EF%BC%9A546-561$$$37156877.jpg');)
;)
;)
;)
%201124-1138.$$$35908550.jpg');)
%20766-780.$$$37100057.jpg');)
%20418-432.$$$36893736.jpg');)
%EF%BC%9A-240-255.$$$35108512.jpg');)
533-545$$$36543525.jpg');)
%201-13.$$$36600053.jpg');)
;)
Succinyl-coenzyme A (succinyl-CoA) is an intermediate in the citric acid cycle.[1] It is converted to succinate, which is a metabolic intermediate with various biological activities. Succinyl-CoA is required, with glycine, to form δ-aminolevulinic acid in the first step of porphyrin and heme synthesis.[2] Succinyl-CoA deficiency, caused by vitamin B12 deficiency can disrupt heme and energy production, leading to neuromotor dysfunction.[3]
Reference:
[1]. Meister, A. ACYL phosphates as enzyme-bound intermediates in the biosynthesis of glutamine, glutathione, succinyl, coenzyme A, and cabamyl phosphate. Trans. N. Y. Acad. Sci. 30(8), 1157-1180 (1968).
[2]. Bonkovsky, H.L., Guo, J.-T., Hou, W., et al. Porphyrin and heme metabolism and the porphyrias. Compr Physiol 3(1), 365-401 (2013).
[3]. Bicakci, Z. Growth retardation, general hypotonia, and loss of acquired neuromotor skills in the infants of mothers with cobalamin deficiency and the possible role of succinyl-CoA and glycine in the pathogenesis. Medicine (Baltimore) 94(9), e584 (2015).
Average Rating: 5 (Based on Reviews and 11 reference(s) in Google Scholar.)
GLPBIO products are for RESEARCH USE ONLY. Please make sure your review or question is research based.
Required fields are marked with *