>>Signaling Pathways>> Ubiquitination/ Proteasome>> Autophagy>>TA 02

TA 02

Catalog No.GC11635

SB 203580의 유사체인 TA 02는 IC50이 20nM인 p38 MAPK 억제제입니다.

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TA 02 Chemical Structure

Cas No.: 1784751-19-4

Size 가격 재고 수량
10mM (in 1mL DMSO)
US$53.00
재고 있음
10mg
US$99.00
재고 있음
50mg
US$297.00
재고 있음

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Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents Related Products

TA-02 is a p38 MAPK inhibitor with IC50 of 20 nM.IC50 value: 20 nMTarget: p38TA-02 is a novel compound with similar cardiogenic properties asSB203580 and SB202190. TA-02 especially inhibits TGFBR-2.

References:
[1]. Laco F, et al. Cardiomyocyte differentiation of pluripotent stem cells with SB203580 analogues correlates with Wnt pathway CK1 inhibition independent of p38 MAPK signaling. J Mol Cell Cardiol. 2015 Mar;80:56-70.
[2]. Filip LACO, et al. 2,4,5-tri-substituted azole-based casein kinase 1 inhibitors as inducers for cardiomyogenesis. WO 2015119579 A1.

리뷰

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Average Rating: 5 ★★★★★ (Based on Reviews and 16 reference(s) in Google Scholar.)

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