TC-DAPK 6 (Synonyms: DAPK inhibitor) |
Catalog No.GC13950 |
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 315694-89-4
Sample solution is provided at 25 µL, 10mM.
Death-associated protein kinase (DAPK) is a serine/threonine protein kinase implicated in diverse programmed cell death pathways. DAPK is a promising target protein for the treatment of ischemic diseases. TC-DAPK 6 is an oxazalone compound that acts as a potent, ATP-competitive, and highly selective death-associated protein kinase (DAPK) inhibitor (IC50 = 69 and 225 nM against DAPK1 and DAPK3, respectively, with 10 μM ATP); while exhibiting much reduced or no activity against a panel of 48 other kinases even at concentrations as high as 10 μM.
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