Tegatrabetan (Synonyms: BC2059) |
| Catalog No.GC39159 |
테가트라베탄(BC2059)은 β-카테닌 길항제입니다. 테가트라베탄은 β-카테닌과 스캐폴드 단백질 트랜스듀신 β-유사 1(TBL1)의 결합을 방해합니다.
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Cas No.: 1227637-23-1
Sample solution is provided at 25 µL, 10mM.
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Tegatrabetan (BC2059) is a β-Catenin antagonist. Tegatrabetan disrupts the binding of β-catenin with the scaffold protein transducin β-like 1 (TBL1)[1].
[1]. Fiskus W, et al. Pre-clinical efficacy of combined therapy with novel β-catenin antagonist BC2059 and histone deacetylase inhibitor against AML cells. Leukemia. 2015 Jun;29(6):1267-78.
Average Rating: 5 (Based on Reviews and 24 reference(s) in Google Scholar.)
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