Thalidomide-O-amido-C3-PEG3-C1-NH2 |
| Catalog No.GC62595 |
Thalidomide-O-amido-C3-PEG3-C1-NH2는 PROTAC 기술에 사용되는 Thalidomide 기반 세레블론 리간드와 3-단위 PEG 링커를 통합하는 합성된 E3 리가제 리간드-링커 접합체입니다.
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Cas No.: 1799711-29-7
Sample solution is provided at 25 µL, 10mM.
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Thalidomide-O-amido-C3-PEG3-C1-NH2 is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and 3-unit PEG linker used in PROTAC technology.
[1]. Lohbeck J, et al. Practical synthesis of a phthalimide-based Cereblon ligand to enable PROTAC development. Bioorg Med Chem Lett. 2016;26(21):5260-5262. doi:10.1016/j.bmcl.2016.09.048
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