>>Analytical Standards>>THJ 018

THJ 018

Catalog No.GC45048

THJ 018 is an analog of JWH 018 where the core indole structure is substituted with an indazole base.

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THJ 018 Chemical Structure

Cas No.: 1364933-55-0

Size 가격 재고 수량
1mg
US$111.00
재고 있음
5mg
US$502.00
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10mg
US$891.00
재고 있음

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Sample solution is provided at 25 µL, 10mM.

Description of THJ 018

THJ 018 is an analog of JWH 018 where the core indole structure is substituted with an indazole base. Though no biological activity has been reported for THJ 018, structurally similar analogs bind to the brain central cannabinoid (CB1) receptors and display agonist properties in functional assays, suggesting that it would have the same in vivo effects as δ9-THC and various synthetic CBs.

Chemical Properties of THJ 018

Cas No. 1364933-55-0 SDF
Canonical SMILES O=C(C1=NN(CCCCC)C2=C1C=CC=C2)C3=C4C(C=CC=C4)=CC=C3
Formula C23H22N2O M.Wt 342.4
Solubility DMF: 10 mg/ml,DMSO: 10 mg/ml,Ethanol: 10 mg/ml,Methanol: 30 mg/ml Storage Store at -20°C
General tips Please select the appropriate solvent to prepare the stock solution according to the solubility of the product in different solvents; once the solution is prepared, please store it in separate packages to avoid product failure caused by repeated freezing and thawing.Storage method and period of the stock solution: When stored at -80°C, please use it within 6 months; when stored at -20°C, please use it within 1 month.
To increase solubility, heat the tube to 37°C and then oscillate in an ultrasonic bath for some time.
Shipping Condition Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request.

Complete Stock Solution Preparation Table of THJ 018

Prepare stock solution
1 mg 5 mg 10 mg
1 mM 2.9206 mL 14.6028 mL 29.2056 mL
5 mM 0.5841 mL 2.9206 mL 5.8411 mL
10 mM 0.2921 mL 1.4603 mL 2.9206 mL
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In vivo Formulation Calculator (Clear solution) of THJ 018

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

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Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

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Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.
3. All of the above co-solvents are available for purchase on the GlpBio website.

Product Documents

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Review for THJ 018

Average Rating: 5 ★★★★★ (Based on Reviews and 26 reference(s) in Google Scholar.)

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