Tilfrinib |
| Catalog No.GC40927 |
Tilfrinib(화합물 4f)는 Brk에 대해 IC50 값이 3.15nM인 강력하고 선택적인 Brk/PTK6 억제제입니다. 틸프리닙은 우수한 항증식 활성을 나타내며 항종양 가능성이 있습니다.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 1600515-49-8
Sample solution is provided at 25 µL, 10mM.
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Tilfrinib is an inhibitor of breast tumor kinase/protein tyrosine kinase 6 (BRK/PTK6; IC50 = 3.15 nM). It is selective for BRK/PTK6 over HER2 (IC50 = 1,300 nM). Tilfrinib inhibits the growth of MCF-7, HS-578/T, and BT-549 breast cancer cells in vitro (GI50s = 0.99, 1.02, and 1.58 μM, respectively).
Average Rating: 5 (Based on Reviews and 22 reference(s) in Google Scholar.)
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