Tominersen sodium |
Catalog No.GC70669 |
Tominersen sodium은 2세대 2′-O-(2-메티옥시에틸) 반의인 과뉴클레오티드로 헌팅턴 단백질(HTT) mRNA를 표적하고 HTT 생성을 효과적으로 억제한다.
Products are for research use only. Not for human use. We do not sell to patients.
Sample solution is provided at 25 µL, 10mM.
References:
[1]. Kordasiewicz HB, et al. Sustained therapeutic reversal of Huntington's disease by transient repression of huntingtin synthesis. Neuron. 2012 Jun 21;74(6):1031-44.
[2]. Tabrizi SJ, et, al. Targeting Huntingtin Expression in Patients with Huntington's Disease. N Engl J Med. 2019 Jun 13;380(24):2307-2316.
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