>>Signaling Pathways>> Membrane Transporter/Ion Channel>> Calcium Channel>>trans-Ned 19

trans-Ned 19

Catalog No.GC16322

NAADP 길항제이자 TPC 차단제인 trans-Ned 19는 낮은 히스타민 농도에 반응하여 인간 제대 정맥 내피 세포(HUVEC)의 칼슘 신호와 쥐의 대동맥 이완을 억제합니다.

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trans-Ned 19 Chemical Structure

Cas No.: 1354235-96-3

Size 가격 재고 수량
1mg
US$45.00
재고 있음
5mg
US$200.00
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10mg
US$302.00
재고 있음

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Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents Related Products

trans-Ned 19, a NAADP antagonist and TPC blocker, suppresses the calcium signal in human umbilical vein endothelial cells (HUVEC) and the rat aorta relaxation in response to low histamine concentrations[1].

References:
[1]. Zharkich IL, et al. Suppression of Histamine-Induced Relaxation of Rat Aorta and Calcium Signaling in Endothelial Cells by Two-Pore Channel Blocker trans-NED19 and Hydrogen Peroxide. Izv Akad Nauk Ser Biol. 2016 Jul;(4):430-438.

리뷰

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