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Tyrothricin

Catalog No.GC18414

티로트리신은 바실러스 브레비스(Bacillus brevis)에서 분리된 폴리펩타이드 항생제 혼합물이며 티로시딘(tyrocidine)과 그라미시딘(gramicidin)으로 구성됩니다.

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Tyrothricin Chemical Structure

Cas No.: 1404-88-2

Size 가격 재고 수량
1mg
US$44.00
재고 있음
5mg
US$121.00
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10mg
US$171.00
재고 있음
25mg
US$269.00
재고 있음

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Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents Related Products

Tyrothricin is a polypeptide antibiotic mixture produced by B. brevis.[1] [2]Tyrothricin is a mixture of tyrocidine and gramicidin that has rapid in vitro bactericidal activity against T. microdentium, T. macrodentium, T. vincentii, T. buccalis, T. mucosum, T. vaginalis, T. cruzi, and L. tropica. Preclinical studies demonstrate that intravenous use of tyrothricin leads to hemolysis-induced lethality (LD50s = 0.4 and 0.3 mg/kg, in dogs and mice, respectively) and damages liver, kidney, and olfactory tissues. Formulations containing tyrothricin are used topically to treat bacterial skin infections. [1][2]

Reference:
[1]. Dubos, R.J., and Hotchkiss, R.D. The production of bactericidal substances by aerobic sporulating bacilli. J. Exp. Med. 73(5), 629-640 (1941).
[2]. Lask, S.A. Tyrothricin as an antibiotic. Arch. Surg. 56(4), 475-483 (1948).

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