VU6012962 |
| Catalog No.GC34320 |
VU6012962는 347 nM의 IC50을 갖는 경구 생체이용 및 CNS-침투성 대사성 글루타메이트 수용체 7 음성 알로스테릭 조절제(mGlu7 NAM)입니다.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 2313526-86-0
Sample solution is provided at 25 µL, 10mM.
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VU6012962 is an orally bioavailable and CNS-penetrant metabotropic glutamate receptor 7 (mGlu7) negative allosteric modulator (NAM) with an IC50 of 347 nM[1].
[1]. Reed CW, et al. Discovery of an orally bioavailable and Central Nervous System (CNS) penetrant mGlu7 NegativeAllosteric Modulator (NAM) in vivo tool compound: N-(2-(1H-1,2,4-triazol-1-yl)-5-(trifluoromethoxy)phenyl)-4-(cyclopropylmethoxy)-3-methoxybenzamide (VU6012962). J Med Chem. 2019 Jan 4.
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