YQ128 |
| Catalog No.GC39311 |
YQ128은 IC50이 0.30 μM인 강력하고 선택적인 2세대 NLRP3(NOD 유사 수용체 P3) 인플라마좀 억제제입니다.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 2454246-18-3
Sample solution is provided at 25 µL, 10mM.
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YQ128 is a potent and selective second-generation NLRP3 (NOD-like receptor P3) inflammasome inhibitor with an IC50 of 0.30 µM. YQ128 significantly and selectively suppresses the production of IL-1β, but not TNF-α, and it can cross the BBB to reach the CNS. YQ128 has anti-inflammatory activity[1].
[1]. Jiang Y, et al. Discovery of Second-Generation NLRP3 Inflammasome Inhibitors: Design, Synthesis, and Biological Characterization. J Med Chem. 2019 Oct 31.
Average Rating: 5 (Based on Reviews and 2 reference(s) in Google Scholar.)
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