Zenarestat |
Catalog No.GC63990 |
Zenarestat는 강력하고 경구 활성인 알도스 환원효소 억제제입니다.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 112733-06-9
Sample solution is provided at 25 µL, 10mM.
Zenarestat is a potent and orally active aldose reductase inhibitor. Zenarestat improves diabetic peripheral neuropathy in Zucker diabetic fatty rats[1].
Zenarestat (3.2, 32 mg/kg; p.o.; daily for 8 weeks) inhibits nerve sorbitol accumulation in a dose-dependent manner[1].
[1]. Shimoshige Y, et al. The effects of zenarestat, an aldose reductase inhibitor, on peripheral neuropathy in Zucker diabetic fatty rats. Metabolism. 2000;49(11):1395-1399.
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