ZXH-1-161 |
| Catalog No.GC64969 |
ZXH-1-161은 MM1.S 야생형 세포에서 IC50 값이 39nM인 강력한 소뇌(CRBN) 조절제입니다. ZXH-1-161은 GSPT1에 대한 선택적 분해 활성이 있습니다. ZXH-1-161은 다발성 골수종 연구에 사용할 수 있습니다.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 2407654-51-5
Sample solution is provided at 25 µL, 10mM.
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ZXH-1-161 is a potent cereblon (CRBN) modulator with an IC50 value of 39 nM in MM1.S wild type cells. ZXH-1-161 has selective degradation activity towards GSPT1. ZXH-1-161 can be used for researching multiple myeloma[1].
[1]. Powell CE, et al. Selective Degradation of GSPT1 by Cereblon Modulators Identified via a Focused Combinatorial Library. ACS Chem Biol. 2020 Oct 16;15(10):2722-2730.
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