L-651,582 (Synonyms: CAI, L-651,582, NSC 609974) |
Catalog No.GC14656 |
L-651,582 (L-651582) is a cytostatic inhibitor of nonvoltage-operated calcium channels and calcium channel-mediated signaling pathways.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 99519-84-3
Sample solution is provided at 25 µL, 10mM.
Carboxyamidotriazole (L 651582) is a blocker of non-voltage dependent calcium channel[1]. Carboxyamidotriazole (L 651582) is a non-cytotoxic anti-tumor drug, which also shows anti-inflammatory activity[2].
References:
[1]. Chen C, et al. Carboxyamidotriazole Synergizes with Bay 43-9006 to Combat Non-Small Cell Lung Cancer through Inhibition of NANOG and Aggravation of Apoptosis. J Pharmacol Exp Ther. 2017 Aug;362(2):219-229.
[2]. Hussain MM, et al. J Clin Oncol. 2003 Dec 1;21(23):4356-63.
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