L202 |
Catalog No.GC90672 |
An ionizable cationic lipid
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 2170488-92-1
Sample solution is provided at 25 µL, 10mM.
L202 is an ionizable cationic lipid (pKa = 6.04) that has been used in the generation of lipid nanoparticles (LNPs) for the delivery of mRNA.1 Intramuscular administration of LNPs containing L202 and encapsulating nucleoside-modified mRNA encoding pre-fusion stabilized severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike glycoprotein, also known as surface glycoprotein, increase plasma levels of IgG antibodies targeting SARS-CoV-2 spike glycoprotein in mice and cynomolgus monkeys.
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