Lansoprazole sulfone N-oxide |
Catalog No.GC52119 |
A potential impurity found in commercial preparations of lansoprazole
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Cas No.: 953787-54-7
Sample solution is provided at 25 µL, 10mM.
Lansoprazole sulfone N-oxide is a potential impurity found in commercial preparations of the proton pump inhibitor lansoprazole.1 It is a degradation product formed under oxidative conditions.2
1.Reddy, G.M., Mukkanti, K., Kumar, T.L., et al.Synthesis and characterization of metabolites and potential impurities of lansoprazole, an antiulcerative drugSynth. Com.38(20)3477-3489(2008) 2.Shankar, G., Borkar, R.M., Suresh, U., et al.Forced degradation studies of lansoprazole using LC-ESI HRMS and 1 H-NMR experiments: In vitro toxicity evaluation of major degradation productsJ. Mass. Spectrom.52(7)459-471(2017)
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