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LY43578

Catalog No.GC70453

LY43578 is an orally active aromatase inhibitor.

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LY43578 Chemical Structure

Cas No.: 26766-35-8

Size Price Stock Qty
5 mg
$43.00
In stock
10 mg
$68.00
In stock

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Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents
LY43578 is an orally active aromatase inhibitor. LY43578 inhibits P-450-dependent p-nitroanisole O-demethylation and ethylmorphine N-demethylation in hepatic microsomes isolated from rat, with the IC50 of 0.3 and 5 μΜ, respectively. LY43578 can be used for neurological disorder study.

References:
[1]. Lindstrom TD, et al. Disposition of the aromatase inhibitor LY56110 and associated induction and inhibition studies in rats, dogs, and monkeys. Fundam Appl Toxicol. 1987;8(4):595-604.
[2]. Gonzalez MI, et al. Injection of an aromatase inhibitor after the critical period of sexual differentiation. Pharmacol Biochem Behav. 1994;47(1):183-186.

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