m-PEG3-CH2COOH |
| Catalog No.GC62365 |
m-PEG3-CH2COOH is a PEG-based based PROTAC linker can be used in the synthesis of PROTACs.
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Cas No.: 16024-60-5
Sample solution is provided at 25 µL, 10mM.
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m-PEG3-CH2COOH is a PEG-based based PROTAC linker can be used in the synthesis of PROTACs.
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
[1]. Chen X, et al. Histidine-Specific Peptide Modification via Visible-Light-Promoted C-H Alkylation. J Am Chem Soc. 2019 Nov 13;141(45):18230-18237.
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