m-PEG5-nitrile |
| Catalog No.GC67182 |
m-PEG5-nitrile is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.
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Cas No.: 81836-41-1
Sample solution is provided at 25 µL, 10mM.
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m-PEG5-nitrile is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
[1]. Saifer MG, et al. Selectivity of binding of PEGs and PEG-like oligomers to anti-PEG antibodies induced by methoxyPEG-proteins. Mol Immunol. 2014 Feb;57(2):236-46.
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