Mal-PEG10-NHS ester |
Catalog No.GC63761 |
Mal-PEG10-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
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Sample solution is provided at 25 µL, 10mM.
Mal-PEG10-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
[1]. Nalawansha DA, et al. PROTACs: An Emerging Therapeutic Modality in Precision Medicine. Cell Chem Biol. 2020;27(8):998-991.
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