Maresin 2-d5 (Synonyms: 13R,14S-diHDHA-d5, 13R,14S-dihydroxy Docosahexaenoic Acid-d5, MaR2-d5) |
| Catalog No.GC47599 |
A neuropeptide with diverse biological activities
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 1639809-46-3
Sample solution is provided at 25 µL, 10mM.
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Maresin 2-d5 (MaR2-d5) contains 5 deuterium atoms at the 21, 21, 22, 22, and 22 positions. It is intended for use as an internal standard for the quantification of MaR2 by GC- or LC-MS. MaR2 is a 13R,14S-dihydroxy DHA formed by recombinant human macrophage 12-lipoxygenase and soluble epoxide hydrolase co-incubated with DHA.1 At 1 ng/mouse, MaR2 was shown to reduce neutrophil infiltration by 40% in a mouse model of peritonitis, and at 10 pM, MaR2 can enhance human macrophage phagocytosis of zymosan A by 90%.1
1.Deng, B., Wang, C.W., Arnardottir, H.H., et al.Maresin biosynthesis and identification of maresin 2, a new anti-inflammatory and pro-resolving mediator from human macrophagesPLoS One9(7)(2014)
Average Rating: 5 (Based on Reviews and 8 reference(s) in Google Scholar.)
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