MARK-IN-4 |
Catalog No.GC70337 |
MARK-IN-4 is a potent microtubule affinity regulating kinase (MARK) inhibitor with an IC50 of 1 nM.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 1990492-86-8
Sample solution is provided at 25 µL, 10mM.
MARK-IN-4 is a potent microtubule affinity regulating kinase (MARK) inhibitor with an IC50 of 1 nM. Inhibition of microtubule affinity regulating kinase (MARK) represents a potentially attractive means of arresting neurofibrillary tangle pathology in Alzheimer's disease.
References:
[1]. Sloman DL, et al. Optimization of microtubule affinity regulating kinase (MARK) inhibitors with improved physical properties. Bioorg Med Chem Lett. 2016;26(17):4362-4366.
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