ML401 |
| Catalog No.GC38820 |
ML401, a potent chemical probe, selectively antagonizes EBI2 (also known as GPR183) with an IC50 of 1.03 nM.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 1597489-14-9
Sample solution is provided at 25 µL, 10mM.
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ML401, a potent chemical probe, selectively antagonizes EBI2 (also known as GPR183) with an IC50 of 1.03 nM. ML401 displays activity in a chemotaxis assay (IC50=6.24 nM). ML401 shows good stability and no toxicity[1].
ML401 shows no toxicity (>50 μM) towards immortalized Fa2-N4 human hepatocytes and non-cytotoxic in MTT in both LnCap and IMR-32 cells (>50 μM)[1].
ML401 shows very good stability in both human plasma and mouse plasma[1].
[1]. Ardecky R, et al. Functional Antagonists of EBI-2. Probe Reports from the NIH Molecular Libraries Program [Internet].
Average Rating: 5 (Based on Reviews and 37 reference(s) in Google Scholar.)
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