MoTP (Synonyms: 4(4Morpholinylbutylthio)phenol) |
Catalog No.GC44245 |
MoTP, known more formally as 4-(4-morpholinobutylthio)phenol, is used to ablate larval melanocytes in zebrafish in order to study melanocyte regeneration.
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Cas No.: 57055-82-0
Sample solution is provided at 25 µL, 10mM.
MoTP, known more formally as 4-(4-morpholinobutylthio)phenol, is used to ablate larval melanocytes in zebrafish in order to study melanocyte regeneration. MoTP is converted to a cytotoxin in cells with high tyrosinase activity, which in the zebrafish embryo are limited to melanoblasts and newly formed melanocytes. The wash-out of MoTP allows regeneration through the proliferation of melanocyte stem cells.
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