MS9427 TFA |
| Catalog No.GC69506 |
MS9427 TFA is an effective PROTAC EGFR degrader, with Kd values of 7.1 nM and 4.3 nM for wild-type EGFR and mutant EGFR L858R, respectively. MS9427 TFA selectively degrades mutant variants through the ubiquitin/proteasome system (UPS) and autophagy/lysosome pathway, but not WT EGFR. MS9427 TFA strongly inhibits NSCLC cell proliferation and can be used in cancer research.
Products are for research use only. Not for human use. We do not sell to patients.
Sample solution is provided at 25 µL, 10mM.
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Review for MS9427 TFA
Average Rating: 5 (Based on Reviews and 30 reference(s) in Google Scholar.)
Review for MS9427 TFA
GLPBIO products are for RESEARCH USE ONLY. Please make sure your review or question is research based.
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