NVS-STG2 |
| Catalog No.GC91777 |
NVS-STG2 is an agonist of stimulator of interferon genes (STING).
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: N/A
Sample solution is provided at 25 µL, 10mM.
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NVS-STG2 is an agonist of stimulator of interferon genes (STING).[1] It binds to STING and induces STING activation in a reporter assay (IC50 = 5.2 µM). Intratumoral injection of NVS-STG2 (400 or 800 µg/animal) reduces tumor volume and increases intratumoral IFN-γ levels in a B16.SIY murine melanoma model.
References:
[1].Li, J., Canham, S.M., Wu, H., et al.Activation of human STING by a molecular glue-like compoundNat. Chem. Biol.20(3)365-372(2024).
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