Home>>Lipids>>PAMAM Dendrimer G0.5 Carboxylate (sodium salt) (water solution)

PAMAM Dendrimer G0.5 Carboxylate (sodium salt) (water solution) (Synonyms: PAMAM G0.5 Carboxylate; Polyamidoamine Dendrimer G0.5 Carboxylate)

Catalog No.GC91461

PAMAM dendrimer G0.5 carboxylate (PAMAM G0.5) is a polyamidoamine (PAMAM) dendrimer with carboxylate termini.

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PAMAM Dendrimer G0.5 Carboxylate (sodium salt) (water solution) Chemical Structure

Cas No.: 339334-01-9

Size Price Stock Qty
500mg
$105.00
In stock
1g
$200.00
In stock

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Sample solution is provided at 25 µL, 10mM.

Description of PAMAM Dendrimer G0.5 Carboxylate (sodium salt) (water solution)

PAMAM dendrimer G0.5 carboxylate (PAMAM G0.5) is a polyamidoamine (PAMAM) dendrimer with carboxylate termini.1 It is approximately 27.9 Å in diameter in water and has 8 surface groups.2 Conjugates of PAMAM G0.5 with the active fragment of the DNA cross-linking agent oxaliplatin are cytotoxic to A2780 ovarian, MCF-7 breast, and Caco-2 colon cancer cells and BJ fibroblasts (IC50s = 0.03, 1.6, 0.18, and 3 µM, respectively).

Chemical Properties of PAMAM Dendrimer G0.5 Carboxylate (sodium salt) (water solution)

Cas No. 339334-01-9 SDF
Synonyms PAMAM G0.5 Carboxylate; Polyamidoamine Dendrimer G0.5 Carboxylate
Formula C46H72N10O20 ? 8Na M.Wt 1269.1
Solubility Water: Soluble Storage Store at -20°C
General tips Please select the appropriate solvent to prepare the stock solution according to the solubility of the product in different solvents; once the solution is prepared, please store it in separate packages to avoid product failure caused by repeated freezing and thawing.Storage method and period of the stock solution: When stored at -80°C, please use it within 6 months; when stored at -20°C, please use it within 1 month.
To increase solubility, heat the tube to 37°C and then oscillate in an ultrasonic bath for some time.
Shipping Condition Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request.

Complete Stock Solution Preparation Table of PAMAM Dendrimer G0.5 Carboxylate (sodium salt) (water solution)

Prepare stock solution
1 mg 5 mg 10 mg
1 mM 0.788 mL 3.9398 mL 7.8796 mL
5 mM 0.1576 mL 0.788 mL 1.5759 mL
10 mM 0.0788 mL 0.394 mL 0.788 mL
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In vivo Formulation Calculator (Clear solution) of PAMAM Dendrimer G0.5 Carboxylate (sodium salt) (water solution)

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

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Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

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Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.
3. All of the above co-solvents are available for purchase on the GlpBio website.

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Average Rating: 5 ★★★★★ (Based on Reviews and 30 reference(s) in Google Scholar.)

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