PAMAM Dendrimer G0.5 Carboxylate (sodium salt) (water solution) (Synonyms: PAMAM G0.5 Carboxylate; Polyamidoamine Dendrimer G0.5 Carboxylate) |
Catalog No.GC91461 |
PAMAM dendrimer G0.5 carboxylate (PAMAM G0.5) is a polyamidoamine (PAMAM) dendrimer with carboxylate termini.
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Cas No.: 339334-01-9
Sample solution is provided at 25 µL, 10mM.
PAMAM dendrimer G0.5 carboxylate (PAMAM G0.5) is a polyamidoamine (PAMAM) dendrimer with carboxylate termini.1 It is approximately 27.9 Å in diameter in water and has 8 surface groups.2 Conjugates of PAMAM G0.5 with the active fragment of the DNA cross-linking agent oxaliplatin are cytotoxic to A2780 ovarian, MCF-7 breast, and Caco-2 colon cancer cells and BJ fibroblasts (IC50s = 0.03, 1.6, 0.18, and 3 µM, respectively).
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