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Penicillin amidase, E. coli

Catalog No.GC72157

Penicillin amidase (EC 3.5.1.11) (Penicillin acylase) is an enzyme that cleaves the acyl side chains of penicillins.

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Penicillin amidase, E. coli Chemical Structure

Cas No.: 9014-06-6

Size Price Stock Qty
100 mg
$86.00
In stock
250 mg
$135.00
In stock

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Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents
Penicillin amidase (EC 3.5.1.11) (Penicillin acylase) is an enzyme that cleaves the acyl side chains of penicillins. Penicillin amidase can be used for the production of 6-aminopenicillanic acid. Penicillin amidase can also be used in the resolution of racemic mixtures, peptide synthesis, and synthesis of semi-synthetic β-lactam antibiotics.

References:
[1]. Duggleby HJ, et al. Penicillin acylase has a single-amino-acid catalytic centre. Nature. 1995 Jan 19;373(6511):264-8.
[2]. Avinash VS, et al. Penicillin acylases revisited: importance beyond their industrial utility. Crit Rev Biotechnol. 2016;36(2):303-16.
[3]. Tishkov VI, et al. Protein engineering of penicillin acylase. Acta Naturae. 2010 Jul;2(3):47-61.

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