Pifusertib hydrochloride (Synonyms: TAS-117 hydrochloride) |
| Catalog No.GC69991 |
Pifusertib (TAS-117) hydrochloride is an effective, selective, and orally active isoform Akt inhibitor (with IC50 values of 4.8, 1.6, and 44 nM for Akt1, 2, and 3 respectively). Pifusertib hydrochloride stimulates anti-myeloma activity and enhances lethal endoplasmic reticulum stress induced by proteasome inhibition. Pifusertib hydrochloride induces apoptosis and autophagy in cells.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 2930090-28-9
Sample solution is provided at 25 µL, 10mM.
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Average Rating: 5 (Based on Reviews and 30 reference(s) in Google Scholar.)
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