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PM-81I

Catalog No.GC71017

PM-81I is a potent STAT6 inhibitor (targeting the SH2 structural domain) that effectively reduces STAT6 phosphorylation levels.

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PM-81I Chemical Structure

Cas No.: 1637532-83-2

Size Price Stock Qty
1 mg
$504.00
In stock

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Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents
PM-81I is a potent STAT6 inhibitor (targeting the SH2 structural domain) that effectively reduces STAT6 phosphorylation levels. PM-81I can be used in studies of allergic lung disease, allergic rhinitis, chronic obstructive pulmonary disease or cancer[1].

PM-81I (0.05, 0.1, 0.5, 1, 2.5, 5 µM; 2 h) inhibits IL-4 stimulated phosphorylation of STAT6 in Bease-2B immortalizedhuman epithelial airway cells[1].

References:
[1]. John S, et al. Stat6 inhibitors. Patent WO2014182928A2.

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