PM-81I |
Catalog No.GC71017 |
PM-81I is a potent STAT6 inhibitor (targeting the SH2 structural domain) that effectively reduces STAT6 phosphorylation levels.
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Cas No.: 1637532-83-2
Sample solution is provided at 25 µL, 10mM.
PM-81I is a potent STAT6 inhibitor (targeting the SH2 structural domain) that effectively reduces STAT6 phosphorylation levels. PM-81I can be used in studies of allergic lung disease, allergic rhinitis, chronic obstructive pulmonary disease or cancer[1].
PM-81I (0.05, 0.1, 0.5, 1, 2.5, 5 µM; 2 h) inhibits IL-4 stimulated phosphorylation of STAT6 in Bease-2B immortalizedhuman epithelial airway cells[1].
References:
[1]. John S, et al. Stat6 inhibitors. Patent WO2014182928A2.
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