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PROTAC IRAK4 degrader-1

Catalog No.GC62197

PROTAC IRAK4 degrader-1 is a Cereblon-based PROTAC interleukin-1 receptor-associated kinase 4 (IRAK4) degrader extracted from patent US20190192668A1 Compound I-210, makes 20-50%, and >50% IRAK4 degradation at 0.01, 0.1, and 1 μM in OCI-LY-10 cells, respectively.

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PROTAC IRAK4 degrader-1 Chemical Structure

Cas No.: 2360533-90-8

Size Price Stock Qty
5 mg
$1,125.00
In stock

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Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents

PROTAC IRAK4 degrader-1 is a PROTAC interleukin-1 receptor-associated kinase 4 (IRAK4) degrader extracted from patent US20190192668A1 Compound I-210, makes 20-50%, and >50% IRAK4 degradation at 0.01, 0.1, and 1 μM in OCI-LY-10 cells, respectively[1].

[1]. Nello Mainolfi, et al. Irak degraders and uses thereof. US20190192668A1.

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