Protease Inhibitor Cocktail (EDTA-Free,100× in DMSO) |
Catalog No.GK10014 |
Protease inhibitor cocktail is used in cell lysates or tissue extracts to increase protein stability.
Products are for research use only. Not for human use. We do not sell to patients.
Sample solution is provided at 25 µL, 10mM.
- J Neuroinflamm 19.1 (2022): 149.PMID:35705998
- Int Immunopharmacol 116 (2023): 109637.PMID:36764283
- Iscience 26.4 (2023).PMID:37035004
- Cell Death Differ 30.3 (2023): 702-715.PMID:36220888
- Front Cell Infect Mi 12 (2022): 877265.PMID:35444960
- Front Pharmacol 13 (2022): 938134.PMID:36210836
- Neural Regen Res 18.12 (2023): 2711-2719.PMID:37449635
- Redox Biol 65 (2023): 102824.PMID:37517320
- Inflamm Res 72.9 (2023): 1773-1787.PMID:37659014
- Acta Bioch Bioph Sin 55.10 (2023): 1561.PMID:37635409
- J Ethnopharmacol (2023): 117537.PMID:38043756
- Adv Funct Mater (2024):2305827.
- Acs Infect Dis (2024).PMID:38317607
- Int Immunopharmacol 130 (2024):111811.PMID:38457929
- Int Immunopharmacol 130 (2024):111750.PMID:38442577
- Cell Commun Signal 22.1 (2024):1-24.PMID:38610001
- Food Funct (2024).PMID:38602356
- Biochem Pharmacol (2024):116230.PMID:38643905
- J Exp Clin Canc Res 43.1 (2024):1-19.PMID:38702792
- J Pharm Pharmacol (2024):rgae060.PMID:38767973
- Mol Med 30.1 (2024):1-14.PMID:38760717
- Mol Med Rep 30.1 (2024):1-11.PMID:38757346
- Acta Crystallogr F (2024).PMID:38818823
- J Control Release 372 (2024):778-794.PMID:38936744
- Biomolecules and Biomedicine (2024).PMID:38958450
- Geroscience (2024):1-18.PMID:38922380
- Skeletal Muscle 14 (2024).PMID:39026344
- Biomol Biomed (2024).PMID:38958450
- Cell Rep 43.8 (2024).PMID:39106181
- Mol Med 30.1 (2024)1-18.PMID:39138413
Protease inhibitor cocktail is used in cell lysates or tissue extracts to increase protein stability.
Endogenous proteins are produced and removed in a balanced state, so their cellular levels are generally stable under stable environmental conditions. However, protein production is greatly halted and degradation is enhanced when cells are studied in vitro. To prevent the degradation of proteins under such conditions, one can utilize a cocktail of inhibitors of those enzymes known to be present.
Protease inhibitor cocktail is used in cell lysates or tissue extracts to increase protein stability. The cocktail functions to inhibit proteases that would degrade either phosphorylated or non-phosphorylated protein substrates.
Protease inhibitor cocktail has been optimized and tested for mammalian cell and tissue extracts. It contains inhibitors with a broad specificity for serine, cysteine, and acid proteases, and aminopeptidases. This cocktail is supplied as a ready-to-use solution in DMSO.
Ingredient | Summary | CAS Number | Targets |
Aprotinin | Inhibitor of bovine pancreatic trypsin | 9087-70-1 | Proteases|Serine Protease |
Bestatin | Aminopeptidase inhibitor | 58970-76-6 | Proteases|Aminopeptidase |
E-64 | Cysteine protease inhibitor,irriversible | 66701-25-5 | Proteases|Cathepsin |
Leupeptin, Microbial | Inhibitor of serine and cysteine proteases | 103476-89-7 | Proteases|Serine Protease |
Pepstatin A | Aspartic proteinases inhibitor | 26305-03-3 | Proteases|Other Proteases |
AEBSF.HCl | Serine protease inhibitor | 30827-99-7 | Proteases|Serine Protease |
Average Rating: 5
(Based on Reviews and 24 reference(s) in Google Scholar.)GLPBIO products are for RESEARCH USE ONLY. Please make sure your review or question is research based.
Required fields are marked with *