Pseudouridine 5'-triphosphate trisodium (Synonyms: Pseudo-UTP trisodium) |
Catalog No.GC65372 |
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Sample solution is provided at 25 µL, 10mM.
Pseudouridine-5'-triphosphate (Pseudo-UTP) is one of the most commonly used modified nucleoside for the polymerase-mediated synthesis of RNA molecules. Compared with uridine-containing unmodified mRNAs, the application of pseudouridine-containing modified mRNAs exhibits better nuclease stability, immunogenicity, and translational properties[1]..
[1]. Muthian Shanmugasundaram, et al. An Efficient Protection-Free One-Pot Chemical Synthesis of Modified Nucleoside-5'-Triphosphates. Nucleosides Nucleotides Nucleic Acids. 2016 Jul 2;35(7):356-62.
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