QR-0217 |
| Catalog No.GC71240 |
QR-0217 is a potent Aβ1-40 aggregation inhibitor with an IC50 value of 7.5 µM.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 1027786-12-4
Sample solution is provided at 25 µL, 10mM.
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QR-0217 is a potent Aβ1-40 aggregation inhibitor with an IC50 value of 7.5 µM. QR-0217 inhibits α-synuclein aggregation. QR-0217 reduces memory impairments caused by Aβ neurotoxicity.
QR-0217 (20, 100 µM; 96 h) inhibits α-synuclein (4 μM) aggregation[1].
QR-0217 (50 µM) significantly rescues impairment of LTP in the APP/PS1 transgenic mice hippocampal slices[1].
References:
[1]. Michael D. Carter, et al. Compounds and methods for treating protein folding disorders. US8362066B2.
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Average Rating: 5 (Based on Reviews and 30 reference(s) in Google Scholar.)
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