Apoptosis
Products for Apoptosis
- Cat.No. Product Name Information
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GC19910
2,2',4,4'-Tetrabromodiphenyl Ether
BDE-47
-
GC63941
α-Solanine
α-solanine, a bioactive component and one of the major steroidal glycoalkaloids in potatoes, has been observed to inhibit growth and induce apoptosis in cancer cells.
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GC67618
α-Tocopherol phosphate disodium
alpha-Tocopherol phosphate disodium; TocP disodium; Vitamin E phosphate disodium
α-Tocopherol phosphate (alpha-Tocopherol phosphate) disodium, a promising antioxidant, can protect against long-wave UVA1 induced cell death and scavenge UVA1 induced ROS in a skin cell model. α-Tocopherol phosphate disodium possesses therapeutic potential in the inhibition of apoptosis and increases the migratory capacity of endothelial progenitor cells under high-glucose/hypoxic conditions and promotes angiogenesis. -
GC64619
β-Ionone
β-Ionone is effective in the induction of apoptosis in gastric adenocarcinoma SGC7901 cells. Anti-cancer activity.
-
GC72061
β-Phellandrene
β-Phellandrene is obtained from Carum petroselinum.
-
GC45277
(±)-Camphene
DL-Camphene, NSC 4165
-
GC40218
(-)-Epigallocatechin Gallate-d3/d4
EGCG-d3/d4
(-)-Epigallocatechin gallate-d3/d4 is intended for use as an internal standard for the quantification of (-)-epigallocatechin gallate by GC- or LC-MS. -
GC41698
(D)2-Rh 110 (trifluoroacetate salt)
D2R, (Asp)2-Rhodamine 110, Rhodamine 110 bis-(L-aspartic acid amide)
(D)2-Rh 110 is a fluorogenic caspase substrate. -
GC72216
(Gly14)-Humanin (human) (acetate)
(Gly14)-Humanin (human) (14-Glycine-Humanin (human)) acetate is an analog of Humanin in which the 14th amino acid serine was replaced with glycine (Gly).
-
GC72915
(R)-MRT199665
(R)-MRT199665 is an isomer of MRT199665.
-
GC52192
(S)-4'-nitro-Blebbistatin
(-)-4'-nitro-Blebbistatin, p-nitro-Blebbistatin, para-nitro-Blebbistatin
(S)-4'-nitro-Blebbistatin is a non-cytotoxic, photostable, fluorescent and specific Myosin II inhibitor, usd in the study of the specific role of myosin II in physiological, developmental, and cell biological studies. -
GC40121
(Z-DEVD)2-Rh 110 (trifluoroacetate salt)
(Z-Asp-Glu-Val-Asp)2-Rhodamine 110
(Z-DEVD)2-Rh 110 is a fluorogenic substrate for caspase-3. -
GC41742
(Z-IETD)2-Rh 110 (trifluoroacetate salt)
(Z-Ile-Glu-Thr-Asp)2-R110, Rhodamine 110 bis-(N-CBZ-IETD)2
(Z-IETD)2-Rh 110 is a fluorogenic substrate for caspase-8. -
GC19824
(±)-Pinocembrin
(+)-Pinocembrin, Dihydrochrysin, NSC 279005
(±)-Pinocembrin ((±)-5,7-Dihydroxyflavanone) is a GPR120 ligand able to promote wound healing in HaCaT cell line. -
GC92074
1,2,3-Trioleoyl Glycerol-d5
Glyceryl Trioleate-d5; TG(18:1/18:1/18:1)-d5; Triolein-d5
1,2,3-Trioleoyl glycerol-d5 is intended for use as an internal standard for the quantification of 1,2,3-trioleoyl glycerol by GC- or LC-MS. -
GC70375
12-HETE-d8
12-HETE-d8 is the deuterium labeled 12-HETE.
-
GC26213
13,14-Dihydro-13-methyl[1,3]benzodioxolo[5,6-c]-1,3-dioxolo[4,5-i]phenanthridine-14-carbonitrile
DIHYDROSANGUINARINE
-
GC40452
15(S)-HETE MaxSpec® Standard
15(S)-HETE is a major arachidonic acid metabolite from the 15-lipoxygenase pathway.
-
GC68452
2,4,6-Triiodophenol
-
GC62777
2-Methoxy-4-vinylphenol
2-Methoxy-4-vinylphenol (2M4VP), a naturally Germination inhibitor, exerts potent anti-inflammatory effects.
-
GC68043
2-tert-Butyl-1,4-benzoquinone
-
GC48449
28-(Poc-amino)betulin
-
GC62033
3α-Hydroxy pravastatin sodium
3α-Isopravastatin, R-416
3α-Hydroxy pravastatin sodium is the major metabolite of Pravastatin. -
GC20020
3,4-Dihydroxyflavone
3',4'-DHF
-
GC42240
3,6-dichloro-benzo[b]thiophene-2-Carboxylic Acid
3,6-dichloro-benzo[b]thiophene-2-Carboxylic acid is an inhibitor of myeloid cell leukemia 1 (Mcl-1) with a Ki value of 59 μM for binding of FITC-Mcl-1-BH2 peptide binding to Mcl-1.
-
GC64762
3,6-Dihydroxyflavone
3,6-Dihydroxyflavone is an anti-cancer agent. 3,6-Dihydroxyflavone dose- and time-dependently decreases cell viability and induces apoptosis by activating caspase cascade, cleaving poly (ADP-ribose) polymerase (PARP). 3,6-Dihydroxyflavone increases intracellular oxidative stress and lipid peroxidation.
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GC74668
3-Methoxy-9H-Carbazole
3-Methoxy-9H-Carbazole induces caspase-3 activities and the cellular generation of eactive oxygen species.
-
GC71507
5'-Methylthioadenosine-13C6
5'-Methylthioadenosine-13C6 is the 13C-labeled 5'-Methylthioadenosine.
-
GC52227
5-(3',4'-Dihydroxyphenyl)-γ-Valerolactone
(±)-δ-(3,4-Dihydroxyphenyl)-γ-Valerolactone, 5-(3',4'-Dihydroxyphenyl)-γ-VL
An active metabolite of various polyphenols -
GC90889
5-(3'-Hydroxyphenyl)-γ-Valerolactone
A metabolite of various polyphenols
-
GC68562
5-Aminolevulinic acid-13C-1 hydrochloride
5-ALA-13C-1 hydrochloride; δ-Aminolevulinic acid-13C-1 hydrochloride; 5-Amino-4-oxopentanoic acid-13C-1 hydrochloride
5-Aminolevulinic acid-13C-1 (5-ALA-13C-1) hydrochloride is a 13C-labeled form of 5-Aminolevulinic acid hydrochloride. 5-Aminolevulinic acid hydrochloride (5-ALA hydrochloride) is an intermediate in the biosynthesis of heme in the body and serves as a precursor to porphyrins.
-
GC71833
5-Aminolevulinic acid-d2 hydrochloride
5-Aminolevulinic acid-d2 (hydrochloride) is deuterium labeled 5-Aminolevulinic acid (hydrochloride).
-
GC63958
6α-Hydroxy Paclitaxel-d5
6α-Hydroxy Paclitaxel-d5 is the deuterium labeled 6α-Hydroxy paclitaxel. 6α-Hydroxy paclitaxel is a primary metabolite of Paclitaxel. 6α-Hydroxy paclitaxel retains a time-dependent effect on organic anion-transporting polypeptides 1B1/SLCO1B1 (OATP1B1) with similar inhibition potency to Paclitaxel, whereas it no longer showed time-dependent inhibition of OATP1B3. 6α-Hydroxy paclitaxel can be used for the research of cancer.
-
GC70659
9-cis-Retinoic acid-d5
9-cis-Retinoic acid-d5 is the deuterium labeled 9-cis-Retinoic acid.
-
GC73269
ABBV-467
ABBV-467 is a selective MCL-1 inhibitor (Ki: <0.01 nM).
-
GC42677
ABO (hydrochloride)
ABO is a modulator of annexin A7.
-
GC49745
ABT-263-d8
Navitoclax-d8
ABT-263-d8 is the deuterium labeled Navitoclax. Navitoclax (ABT-263) is a potent and orally active Bcl-2 family protein inhibitor that binds to multiple anti-apoptotic Bcl-2 family proteins, such as Bcl-xL, Bcl-2 and Bcl-w, with a Ki of less than 1 nM. -
GC70733
ABT-510 acetate
ABT-510 acetate is an anti-angiogenic TSP peptide (Thrombospondin-1 analogue) that induces apoptosis and inhibits ovarian tumour growth in an orthotopic, syngeneic model of epithelial ovarian cancer.
-
GC90489
AC 187 (trifluoroacetate salt)
An antagonist of calcitonin and amylin receptors
-
GC40122
Ac-AAVALLPAVLLALLAP-DEVD-CHO (trifluoroacetate salt)
Ac-Ala-Ala-Val-Ala-Leu-Leu-Pro-Ala-Val-Leu-Leu-Ala-Leu-Leu-Ala-Pro-Asp-Glu-Val-Asp-CHO, Ac-AAVALLPAVLLALLAP-DEVD-aldehyde, Ac-AAVALLPAVLLALLAPDEVD-CHO, Caspase-3 Inhibitor I, DEVD-CHO-CPP 32
Ac-AAVALLPAVLLALLAP-DEVD-CHO is a composite of Ac-DEVD-CHO, a peptide inhibitor of caspase-3 and -7, and a cell-permeable hydrophobic sequence derived from K-FGF. -
GC40118
Ac-AAVALLPAVLLALLAP-IETD-CHO (trifluoroacetate salt)
Ac-Ala-Ala-Val-Ala-Leu-Leu-Pro-Ala-Val-Leu-Leu-Ala-Leu-Leu-Ala-Pro-Ile-Glu-Thr-Asp-CHO, Caspase-8 Inhibitor I
Ac-AAVALLPAVLLALLAP-IETD-CHO is a composite of Ac-IETD-CHO, a peptide inhibitor of caspase-8, and a cell-permeable hydrophobic sequence derived from K-FGF. -
GC40123
Ac-AAVALLPAVLLALLAP-VAD-CHO (trifluoroacetate salt)
Caspase Inhibitor II, Ac-AAVALLPAVLLALLAP-VAD-aldehyde, Ac-AAVALLPAVLLALLAPVAD-CHO
Ac-AAVALLPAVLLALLAP-VAD-CHO is a composite of Ac-VAD-CHO, a non-selective caspase inhibitor, and a cell-permeable hydrophobic sequence derived from K-FGF. -
GC48430
Ac-DEVD-CMK (trifluoroacetate salt)
AcAspGluValAspCMK, Caspase3 Inhibitor III
-
GC42687
Ac-DMQD-AMC (trifluoroacetate salt)
Ac-Asp-Met-Gln-Asp-AMC, Ac-Asp-Met-Gln-Asp-7-amino-4-methylcoumarin
Ac-DMQD-AMC is a fluorogenic substrate for caspase-3. -
GC42688
Ac-DMQD-CHO (trifluoroacetate salt)
Ac-Asp-Met-Gln-Asp-CHO, Caspase-3 Inhibitor
Ac-DMQD-CHO is a peptide inhibitor of caspase-3 (IC50 = 39 nM). -
GC40154
Ac-ESMD-CHO (trifluoroacetate salt)
Ac-Glu-Ser-Met-Asp-CHO
Ac-ESMD-CHO is an inhibitor of caspase-3 maturation. -
GC40152
Ac-IEPD-pNA (trifluoroacetate salt)
Ac-Ile-Glu-Pro-Asp-p-nitroanilide, Caspase-8 Chromogenic Substrate, Granzyme B Substrate VIII
Ac-IEPD-pNA is a colorimetric substrate for granzyme B and caspase-8. -
GC40164
Ac-IETD-CHO (trifluoroacetate salt)
Caspase-8 Inhibitor
Ac-IETD-CHO is an inhibitor of caspase-8 (IC50 = 5 nM).
-
GC42708
Ac-LEHD-AFC (trifluoroacetate salt)
N-Acetyl-Leu-Glu-His-Asp-7-amino-4-Trifluoromethylcoumarin, Caspase-9 substrate (Fluorogenic)
Ac-LEHD-AFC is a fluorogenic substrate that can be cleaved by caspase-4, -5, and -9. -
GC46791
Ac-LEHD-pNA (trifluoroacetate salt)
Ac-Leu-Glu-His-Asp-pNA, Caspase-9 Chromogenic Substrate I
A neuropeptide with diverse biological activities -
GC42709
Ac-LEVD-CHO (trifluoroacetate salt)
Ac-Leu-Glu-Val-Asp-CHO, Caspase-4 Inhibitor I
Ac-LEVD-CHO is a caspase-4 inhibitor.
-
GC52372
Ac-VDVAD-AFC (trifluoroacetate salt)
N-Acetyl-Val-Asp-Val-Ala-Asp-AFC, N-Acetyl-Val-Asp-Val-Ala-Asp-7-amino-4-Trifluoromethylcoumarin, Caspase-2 Substrate (Fluorogenic)
A fluorogenic substrate for caspase-2 -
GC42716
Ac-VDVAD-pNA (trifluoroacetate salt)
Ac-Val-Asp-Val-Ala-Asp-pNA, Caspase-2 Chromogenic Substrate, acetyl-Val-Asp-Val-Ala-Asp-p-nitroanilide, acetyl-VDVAD-p-nitroanilide
Ac-VDVAD-pNA is a colorimetric substrate for caspase-2. -
GC42718
Ac-VEID-CHO (trifluoroacetate salt)
Ac-Val-Glu-Ile-Asp-CHO
Ac-VEID-CHO is an inhibitor of caspase-6 (IC50 = 16.2 nM). -
GC40162
Ac-VEID-pNA (trifluoroacetate salt)
Ac-Val-Glu-Ile-Asp-pNA, Ac-Val-Glu-Ile-Asp-p-nitroanilide, Caspase-6 Chromogenic Substrate
Ac-VEID-pNA is a substrate for caspase-6. -
GC70584
Actinomycin X2
Actinomycin X2 (Actinomycin V), produced by many Streptomyces sp.
-
GC74501
Adebrelimab
SHR-1316
Adebrelimab (SHR-1316) is a humanized IgG4 monoclonal PD-L1 (PD-1/PD-L1) antibody. -
GC68632
AK-778-XXMU
AK-778-XXMU is an effective inhibitor of DNA binding 2 (ID2) antagonist, with a KD of 129 nM. AK-778-XXMU can inhibit the migration and invasion of glioma cell lines, induce apoptosis, and more importantly, slow down tumor growth.
-
GC19897
Albendazole Sulfone
ABZ-SO2, ABZ-SOO
Analytical Standards
-
GC40094
all-trans Retinoic Acid-d5
atRA-d5, RA-d5, Vitamin A Acid-d5
all-trans Retinoic acid-d5 is intended for use as an internal standard for the quantification of all-trans retinoic acid by GC- or LC-MS. -
GC63932
Amsilarotene
Amsilarotene (TAC-101; Am 555S), an orally active synthetic retinoid, has selective affinity for retinoic acid receptor α (RAR-α) binding with Ki of 2.4, 400 nM for RAR-α and RAR-β. Amsilarotene induces the apoptotic of human gastric cancer, hepatocellular carcinoma and ovarian carcinoma cells. Amsilarotene can be used for the research of cancer.
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GC73309
Anti-melanoma agent 1
Anti-melanoma agent 1 (Compound 5m) is an anti-melanoma agent and induces cell apoptosis.
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GC91176
AOH1996
An inhibitor of PCNA
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GC74102
Apomine
SR-45023A; SR 9223i; SK&F-99085
Apomine (SR-45023A) is an antineoplastic agent that inhibits the mevalonate/isoprenoid pathway in cholesterol synthesis. -
GC65004
Apostatin-1
Apt-1
Apostatin-1 (Apt-1) is a potent TRADD inhibitor. -
GC70759
AQX-435
AQX-435 is a potent SHIP1 phosphatase activator.
-
GC65163
Ardisiacrispin B
Ardisiacrispin B displays cytotoxic effects in multi-factorial drug resistant cancer cells via ferroptotic and apoptotic cell death.
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GC73077
ARI-1
ARI-1 is an inhibitor of receptor tyrosine kinase-like orphan receptor 1 (ROR1) inhibitor.
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GC60601
ARRY-382
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GC74029
ASCT2-IN-1
ASCT2-IN-1 (compound 20k) is an ASCT2 inhibitor with IC50 values of 5.6 μM and 3.5 μM in cells A549 and HEK293, respectively.
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GC74030
ASCT2-IN-2
ASCT2-IN-2 (compound 25e) is an ASCT2 inhibitor with IC50 of 5.14 μM.
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GC71258
ASK1-IN-4
ASK1-IN-4 (Compound 17) is an ASK1 inhibitor (IC50=0.2 μM).
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GC72803
Aspidin BB
Aspidin BB is a phloroglucinol derivative, which can be isolated from the aerial part of Dryopteris championii.
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GC68700
ASR-488
ASR-488 can activate mRNA binding protein CPEB1, induce apoptosis and inhibit the growth of bladder cancer cells.
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GC73939
ATPase-IN-3
ATPase-IN-3 (compound 6) is a ATPase inhibitor.
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GC72319
Atrosab
Atrosab is a humanized IgG1 antagonistic anti-TNFR1 antibody.
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GC72858
Avenanthramide A
Avenanthramide A is a ptoalexin, which can be found in oats (Avena sativa L.
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GC72868
AZA197
AZA197 is a selective small molecule inhibitor of Cdc42.
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GC64938
AZD-7648
AZD-7648 is a potent, orally active, selective DNA-PK inhibitor with an IC50 of 0.6 nM. AZD-7648 induces apoptosis and shows antitumor activity.
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GC73016
AZD4877
AZD4877 is another isostere to Ispinesib and also a kinesin spindle protein (Eg5) inhibitor with IC50 of 2 nM.
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GC72817
BAI1 hydrochloride
BAI1 drochloride is a selective apoptosis factor BAX allosteric inhibitors.
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GC52344
Bak BH3 (72-87) (human) (trifluoroacetate salt)
A Bak-derived peptide
-
GC52476
Bax Inhibitor Peptide V5 (trifluoroacetate salt)
BIP V5, VPMLK
A Bax inhibitor -
GC68744
BC-?1258
BC-1258 is an activator of F-box/LRR-repeat protein 2 (FBXL2) that stabilizes and upregulates FBXL2 levels. BC-1258 induces apoptosis in tumor cells and significantly inhibits tumor formation in mice.
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GC73928
BDM19
BDM19 binds and activates cytosolic BAX dimers, and prompts cell apoptosis either alone or in combination with BCL-2/BCL-XL inhibitor Navitoclax.
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GC72851
Belapectin
GR-MD-02
Belapectin (GR-MD-02) is a Galectin-3 (Gal-3) inhibitor. -
GC64354
Bendamustine
Bendamustine (SDX-105 free base), a purine analogue, is a DNA cross-linking agent. Bendamustine activates DNA-damage stress response and apoptosis. Bendamustine has potent alkylating, anticancer and antimetabolite properties.
-
GC46914
Bendamustine-d4 (hydrochloride)
A neuropeptide with diverse biological activities
-
GC74515
Benufutamab
GEN1029
Benufutamab (GEN1029) is a death receptor 5 (DR5)-specific agonistic antibody. -
GC70742
Betamethasone-d5-1
Betamethasone-d5-1 is deuterium labeled Betamethasone.
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GC73940
BFC1108
BFC1108 is a small molecule Bcl-2 functional converter.
-
GC68757
BH3 hydrochloride
BH3 hydrochloride is a peptide that can penetrate the blood-brain barrier. It induces cell apoptosis by directly activating pro-apoptotic Bax/Bak or neutralizing anti-apoptotic Bcl-2 proteins (Bcl-2, Bcl-XL, Bcl-w, mcl1 and A-1) through binding to the BH3 domain.
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GC49513
Bim/BOD (IN) Polyclonal Antibody
For immunodetection of Bim-
related proteins -
GC52355
BimS BH3 (51-76) (human) (trifluoroacetate salt)
DMRPEIWIAQELRRIGDEFNAYYARR-OH, Bims (51-76)
A Bim-derived peptide -
GC68769
Biotin-COG1410 TFA
Biotin-COG1410 TFA is a biotinylated form of COG1410, which is a derivative peptide of apolipoprotein E and an apoptosis inhibitor. COG1410 has been shown to have neuroprotective and anti-inflammatory effects in a mouse model of traumatic brain injury (TBI). COG1410 can be used for research on neurological disorders.
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GC40155
Biotin-DEVD-CHO (trifluoroacetate salt)
Biotin-Asp-Glu-Val-Asp-CHO
Biotin-DEVD-CHO is a biotin-conjugated form of the caspase-3 and -7 inhibitor Ac-DEVD-CHO. -
GC68308
Bisdemethoxycurcumin-d8
Curcumin III-d8; Didemethoxycurcumin-d8
-
GC68774
Bleomycin A5
Pingyangmycin
Bleomycin A5 (Pingyangmycin) is a glycopeptide antibiotic with oral activity. Bleomycin A5 has anti-tumor, apoptosis-inducing and bacterial metabolite effects.
-
GC65428
BLM-IN-1
BLM-IN-1 (compound 29) is an effective Bloom syndrome protein (BLM) inhibitor, with a strong BLM binding KD of 1.81 μM and an IC50 of 0.95 μM for BLM. Induces DNA damage response, as well as apoptosis and proliferation arrest in cancer cells.
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GC73893
BLU-222
BLU-222 is an orally active and highly selective CDK2 inhibitor.