A2AR-agonist-1 (Synonyms: JMF 1907) |
| Catalog No.GC30987 |
An agonist of adenosine A2A receptor and inhibitor of ENT1
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 41552-95-8
Sample solution is provided at 25 µL, 10mM.
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A2AR-agonist-1 is a potent A2AR and ENT1 agonist with Ki of 4.39 and 3.47 for A2AR and ENT1.IC50 value: 4.39 and 3.47 (Ki) [1]Target: A2AR and ENT1A2AR-agonist-1 is a novel dual-action compound, targeting the Adenosine A2A Receptor and Adenosine Transporter for Neuroprotection.[1]
[1]. Chen JB, et al. Design and synthesis of novel dual-action compounds targeting the adenosine A(2A) receptor and adenosine transporter for neuroprotection. ChemMedChem. 2011 Aug 1;6(8):1390-1400. [2]. Lin Yun-Lian, et al. Dual-action compounds targeting adenosine A2A receptor and adenosine transporter for prevention and treatment of neurodegenerative diseases. From PCT Int. Appl. (2012), WO 2012064340 A1 20120518. [3]. Chen, Chih-Cheng, et al. Methods and compositions for treating pain. From PCT Int. Appl. (2013), WO 2013120078 A1 20130815.
Average Rating: 5 (Based on Reviews and 22 reference(s) in Google Scholar.)
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