GSK 2250665A |
| Catalog No.GC50156 |
Itk inhibitor
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 1246030-96-5
Sample solution is provided at 25 µL, 10mM.
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Itk inhibitor (pKi = 9.2). Exhibits selectivity for Itk over Aurora B kinase and Btk (pIC50 values are 6.4 and 6.5, respectively) and a panel of other kinases. Inhibits IFNγ production in PBMCs.
Alder et al (2013) Identification of a novel and selective series of Itk inhibitors via a template-hopping strategy. ACS Med.Chem.Lett. 12 948 PMID:24900590
Review for GSK 2250665A
Average Rating: 5 (Based on Reviews and 26 reference(s) in Google Scholar.)
Review for GSK 2250665A
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