Innate Immunity
Products for Innate Immunity
- Cat.No. Product Name Information
-
GC45206
α-GalCer analog 8
α-Galactosylceramide analog 8
α-Galactosylceramide analog 8 (α-GalCer analog 8) is a triazole derivative of α-galactosylceramide.
-
GC48292
α-MSH (human, mouse, rat, porcine, bovine, ovine) (trifluoroacetate salt)
α-Melanocyte-stimulating Hormone, Ac-SYSMEHFRWGKPV-NH2
α-MSH (α-Melanocyte-Stimulating Hormone) TFA, an endogenous neuropeptide, is an endogenous melanocortin receptor 4 (MC4R) agonist with anti-inflammatory and antipyretic activities. -
GC41499
α-Phellandrene
p-Mentha-1,5-diene, (±)-α-Phellandrene
α-Phellandrene is a cyclic monoterpene that has been found in various plants, including Cannabis, and has diverse biological activities. -
GC48920
β-Carboline-1-carboxylic Acid
1-Formic Acid-β-carboline
An alkaloid with diverse biological activities -
GC48298
β-Defensin-2 (human) (trifluoroacetate salt)
hBD-2
An antimicrobial peptide -
GC45230
β-Defensin-3 (human) (trifluoroacetate salt)
hBD-3
β-Defensin-3 is a peptide with antimicrobial properties that protects the skin and mucosal membranes of the respiratory, genitourinary, and gastrointestinal tracts. -
GC45231
β-Defensin-4 (human) (trifluoroacetate salt)
hBD-4 (human)
β-Defensin-4 is a peptide with antimicrobial properties that protects the skin and mucosal membranes of the respiratory, genitourinary, and gastrointestinal tracts. -
GC72061
β-Phellandrene
β-Phellandrene is obtained from Carum petroselinum.
-
GC52010
(±)-10-hydroxy-12(Z),15(Z)-Octadecadienoic Acid
αHYA, (±)-10-hydroxy-12(Z),15(Z)-ODE
An oxylipin gut microbiota metabolite -
GC91298
(±)-Linalool-d3
An internal standard for the quantification of (±)-linalool
-
GC40466
(±)11(12)-EET
(±)11,12-EpETrE
(±)11(12)-EET is a fully racemic version of the R/S enantiomeric forms biosynthesized from arachidonic acid by cytochrome P450 enzymes.
-
GC45922
(±)11(12)-EET-d11 methyl ester
(±)11,12-EpETrE-d11 methyl ester
A neuropeptide with diverse biological activities -
GC40802
(±)12(13)-DiHOME
Isoleukotoxin diol
(±)12(13)-DiHOME is the diol form of (±)12(13)-EpOME, a cytochrome P450-derived epoxide of linoleic acid also known as isoleukotoxin.
-
GC46256
(±)12(13)-DiHOME-d4
Isoleukotoxin diold4
A neuropeptide with diverse biological activities -
GC41288
(±)17(18)-EpETE-Ethanolamide
17,18-EEQ-EA, (±)17,18-EEQ-Ethanolamide, (±)17(18)-EpETE-EA, 17,18-epoxy-Eicosatetraenoic Acid Ethanolamide
(±)17(18)-EpETE-Ethanolamide is an ω-3 endocannabinoid epoxide. -
GC40362
(±)18-HEPE
(±)18-HEPE is produced by non-enzymatic oxidation of EPA.
-
GC41655
(±)19(20)-EDP Ethanolamide
19,20-DHEA epoxide, 19,20-epoxy Docosapentaenoic Acid Ethanolamide, 19,20-EDP-EA, 19,20-EDP epoxide
(±)19(20)-EDP ethanolamide is an ω-3 endocannabinoid epoxide and cannabinoid (CB) receptor agonist (EC50s = 108 and 280 nM for CB1 and CB2, respectively). -
GC40801
(±)9(10)-DiHOME
Leukotoxin diol
Leukotoxin is the 9(10) epoxide of linoleic acid, generated by neutrophils during the oxidative burst. -
GC40540
(±)9(10)-EpOME
Coronaric Acid, (±)9,10EODE, Leukotoxin
(±)9(10)-EpOME is the 9,10-cis epoxide of linoleic acid, generated by neutrophils during the oxidative burst. -
GC40218
(-)-Epigallocatechin Gallate-d3/d4
EGCG-d3/d4
(-)-Epigallocatechin gallate-d3/d4 is intended for use as an internal standard for the quantification of (-)-epigallocatechin gallate by GC- or LC-MS. -
GC45272
(-)-Rasfonin
TT-1
-
GC41712
(R)-3-hydroxy Myristic Acid
(R)-3-hydroxy Tetradecanoic Acid
Lipopolysaccharides (LPS) are components of the cell walls of Gram-negative bacteria. -
GC18773
(Rac)-Benpyrine
A racemate of Benpyrine, is a potent and orally active TNF-α inhibitor
-
GC46352
(S)-DO271
An inactive control for DO264
-
GC41740
(S)-p38 MAPK Inhibitor III
(S)-p38 MAP Kinase Inhibitor III, (S)-p38 Mitogen-activated Protein Kinase Inhibitor III
(S)-p38 MAPK inhibitor III is a methylsulfanylimidazole that inhibits p38 MAP kinase (IC50 = 0.90 μM in vitro). -
GC19824
(±)-Pinocembrin
(+)-Pinocembrin, Dihydrochrysin, NSC 279005
(±)-Pinocembrin ((±)-5,7-Dihydroxyflavanone) is a GPR120 ligand able to promote wound healing in HaCaT cell line. -
GC20028
(±)12(13)-DiHOME MaxSpec® Standard
Isoleukotoxin diol
-
GC49768
1,1’-Ethylidene-bis-(L-tryptophan)
Peak 97 Contaminant, Peak E Contaminant, Peak E Substance
A potential impurity found in commercial preparations of L-tryptophan -
GC41855
1,3-Distearoyl-2-Oleoyl-rac-glycerol
1,3-Distearin-2-Olein, TG(18:0/18:1/18:0)
1,3-Distearoyl-2-oleoyl-rac-glycerol is a triacylglycerol that contains stearic acid at the sn-1 and sn-3 positions and oleic acid at the sn-2 position. -
GC49294
1-(4-Chlorobenzhydryl)piperazine
N-(p-Chlorobenzhydryl)-piperazine, Norchlorcyclizine, NSC 86164
An inactive metabolite of meclizine and chlorcyclizine -
GC41986
1-Arachidonoyl Lysophosphatidic Acid (ammonium salt)
1-Arachidonoyl LPA, 1-Arachidonoyl-sn-glycero-3-phosphate, 1-Eicosatetraenoyl-sn-glycero-3-PA, 20:4 Lyso PA, LPA(20:4), PA(20:4/0:0)
1-Arachidonoyl lysophosphatidic acid is a phospholipid containing arachidonic acid at the sn-1 position.
-
GC46481
1-Hydroxyphenazine
Hemipyocyanine, NSC 88882
A P. aeruginosa virulence factor -
GC41998
1-Methyl-4-imidazoleacetic Acid (hydrochloride)
Methylimidazoleacetic Acid, MIMA, MIAA
1-Methyl-4-imidazoleacetic acid (MIMA) is a stable metabolite of histamine that is produced by the oxidation of the primary metabolite, N-methylhistamine. -
GC19514
1-Methyl-L-tryptophan
NSC 77678, L-1-Methyltryptophan, 1-L-MT, L-1MT
-
GC40910
1-Oleoyl-2-hydroxy-sn-glycero-3-PE
18:1 LPE, 18:1 Lyso-PE, 1-Oleoyl-2-hydroxy-sn-glycero-3-phosphoethanolamine
1-Oleoyl-2-hydroxy-sn-glycero-3-PE is a naturally-occurring lysophospholipid and an analog of plasmalogen lysophosphatidylethanolamine. -
GC42026
1-Palmitoyl-2-hydroxy-sn-glycero-3-PC
1-Hexadecanoyl-sn-glycero-3-Phosphatidylcholine, 1-Hexadecanoyl-sn-glycero-3-Phosphocholine, 1-Hexadecanoyl-sn-glycerol-3-Phosphorylcholine, Lyso-PC, 1-Palmitoyl-sn-glycero-3-Phosphocholine, PC(16:0/0:0), 16:0/0:0-PC
1-Palmitoyl-2-hydroxy-sn-glycero-3-PC is an abundant gonadal LPC (lysophosphatidylcholine). -
GC42035
1-Palmitoyl-2-Stearoyl-3-Oleoyl-rac-glycerol
1-Palmitin-2-Stearin-3-Olein, TG(16:0/18:0/18:1)
1-Palmitoyl-2-stearoyl-3-oleoyl-rac-glycerol is a triacylglycerol that contains palmitic, stearic, and oleic acid at the sn-1, sn-2, and sn-3 positions, respectively. -
GC46490
1-Palmitoyl-d3-2-hydroxy-sn-glycero-3-PC
1-Hexadecanoyl-sn-glycero-3-Phosphatidylcholine-d3, 1-Hexadecanoyl-sn-glycero-3-Phosphocholine-d3, LPC-d3, 16:0/0:0(d3) Lyso-PC, 1-Palmitoyl-sn-glycero-3-Phosphocholine-d3, PC(16:0/0:0)-d3, 16:0/0:0-PC-d3
A neuropeptide with diverse biological activities -
GC45693
1-Palmitoyl-d9-2-hydroxy-sn-glycero-3-PC
1-Hexadecanoyl-d9-sn-glycero-3-Phosphatidylcholine, 1-Hexadecanoyl-d9-sn-glycero-3-Phosphocholine, 16:0(d9) Lyso-PC, PC(16:0-d9/0:0), 16:0-d9/0:0-PC
A quantitative analytical standard guaranteed to meet MaxSpec® identity, purity, stability, and concentration specifications -
GC49730
1-Stearoyl-2-15(S)-HETE-sn-glycero-3-PE-d11
15(S)-HETE-SAPE-d11, 15(S)-Hydroxyeicosatetraenoic Acid-SAPE-d11, 1-Stearoyl-2-15(S)-HETE-sn-glycero-3-Phosphatidylethanolamine-d11
An internal standard for the quantification of 1-stearoyl-2-15(S)-HETE-sn-glycero-3-PE -
GC41331
1-Stearoyl-2-hydroxy-sn-glycero-3-PC
C18:0-PC, Lyso-PC, 1-Octadecanoyl-2-hydroxy-sn-glycero-3-phosphatidylcholine, PC(18:0/0:0), 1-Stearoyl-2-hydroxy-sn-glycero-3-Phosphocholine, 1-Stearoyl-2-lyso-sn-glycero-3-PC
1-Stearoyl-2-hydroxy-sn-glycero-3-PC is a saturated 18:0 lysophosphatidylcholine found in plasma and oxidized LDL that is thought to play a role in inflammatory diseases and atherosclerosis. -
GC46498
1-Stearoyl-d35-2-hydroxy-sn-glycero-3-PC
S-Lyso-PC-d35, 1-Stearoyl-d35-2-hydroxy-sn-glycero-3-Phosphocholine, 1-Stearoyl-d35-2-lyso-sn-glycero-3-PC
An internal standard for the quantification of 1-stearoyl-2-hydroxy-sn-glycero-3-PC -
GC40971
10(S),17(S)-DiHDHA
10(S),17(S)-DiHDoHE, PDX, Protectin DX
Protectin D1 (also known as neuroprotectin D1 when produced in neuronal tissues) is a DHA-derived dihydroxy fatty acid that exhibits potent protective and anti-inflammatory activities. -
GC41875
11(Z),14(Z)-Eicosadienoic Acid methyl ester
11(Z),14(Z)-Eicosadienoic acid methyl ester is a more lipid soluble form of the ω-6 C20-2 fatty acid 11(Z),14(Z)-eicosadienoic acid, a naturally occurring PUFA.
-
GC41144
11-trans Leukotriene C4
11trans LTC4
11-trans Leukotriene C4 (11-trans LTC4) is a C-11 double bond isomer of LTC4. -
GC52343
113-O12B
An ionizable cationic lipidoid
-
GC18637
11β-Prostaglandin F2α
9α,11βPGF2α, 11βPGF2α, 11epi PGF2α
11β-Prostaglandin F2α (11β-PGF2α) is the primary plasma metabolite of PGD2 in vivo.
-
GC40447
12(R)-HETE
12(R)-Hydroxyeicosatetraenoic Acid
Biosynthesis of 12(R)-HETE in invertebrates is via lipoxygenation of arachidonic acid. -
GC41123
12-epi Leukotriene B4
12epi LTB4
Leukotriene B4 (LTB4) compounds are produced by both enzymatic and non-enzymatic processes. -
GC41096
12-oxo Leukotriene B4
12keto LTB4, 12oxo LTB4
Leukotriene B4 (LTB4) is a dihydroxy fatty acid derived from arachidonic acid through the 5-LO pathway. -
GC49912
13C20,15N10-Cyclic di-GMP (sodium salt)
13C20,15N10-c-di-GMP, 13C20,15N10-Cyclic diguanylate, 13C20,15N10-3’,5’-Cyclic diguanylic Acid
An internal standard for the quantification of cyclic di-GMP -
GC41100
14,15-dehydro Leukotriene B4
14,15dehydro LTB4
Leukotriene B4 (LTB4) is a dihydroxy fatty acid derived from arachidonic acid through the 5-lipoxygenase pathway. -
GC41145
14,15-Leukotriene C4
Eoxin C4, EXC4, 14,15LTC4
Leukotrienes (LTs) are a group of acute inflammatory mediators derived from arachidonic acid in leukocytes. -
GC41148
14,15-Leukotriene D4
Eoxin D4, EXD4, 14,15-LTD4
14,15-Leukotriene D4 (14,15-LTD4) is a member of an alternate class of LTs synthesized by a pathway involving the dual actions of 15- and 12-lipoxygenases (15- and 12-LOs) on arachidonic acid via 15-HpETE and 14,15-LTA4 intermediates. -
GC41150
14,15-Leukotriene E4
Eoxin E4, EXE4, 14,15LTE4
Leukotrienes (LTs) are a group of acute inflammatory mediators derived from arachidonic acid in leukocytes. -
GC41164
15(R)-15-methyl Prostaglandin D2
15(R)15methyl PGD2
15(R)-15-methyl Prostaglandin D2 (15(R)-15-methyl PGD2) is a metabolically stable synthetic analog of PGD2. -
GC41415
15(R)-Lipoxin A4
AT-Lipoxin A4
Lipid-derived lipoxins are produced at the site of vascular and mucosal inflammation where they down-regulate polymorphonuclear leukocyte recruitment and function.
-
GC40451
15(S)-HETE
15(S)-Hydroxyeicosatetraenoic Acid
15(S)-HETE is a major arachidonic acid metabolite from the 15-lipoxygenase pathway. -
GC40452
15(S)-HETE MaxSpec® Standard
15(S)-HETE is a major arachidonic acid metabolite from the 15-lipoxygenase pathway.
-
GC41102
15-deoxy-δ12,14-Prostaglandin D2
15deoxyΔ12,14PGD2
15-deoxy-δ12,14-PGD2 is a synthetic analog of PGD2 and a potential precursor to the PPARγ ligand 15-deoxy-δ12,14-PGJ2. -
GC46443
15-deoxy-δ12,14-Prostaglandin D2-d4
15-deoxy-Δ12,14-PGD2-d4
A neuropeptide with diverse biological activities -
GC46444
15-deoxy-δ12,14-Prostaglandin D2-d9
15-deoxy-Δ12,14-PGD2-d9
A neuropeptide with diverse biological activities -
GC40606
15-keto Prostaglandin E2 MaxSpec® Standard
15-keto Prostaglandin E2 (15-keto PGE2) is a metabolite of PGE2 formed by 15-hydroxy PGDH.
-
GC46449
15-keto Prostaglandin E2-d4
15-keto PGE2-d4, 15-oxo PGE2-d4
A neuropeptide with diverse biological activities -
GC46450
15-keto Prostaglandin E2-d9
15-keto PGE2-d9, 15-oxo PGE2-d9
A neuropeptide with diverse biological activities -
GC49178
17(R)-Protectin D1
Aspirin-triggered Protectin D1, 17-epi Neuroprotectin D1, 17(R)-Neuroprotectin D1, 17(R)-NPD1, 17(R)-PD1, 17-epi Protectin D1
An aspirin-triggered epimer of protectin D1 -
GC41951
17(R)-Resolvin D1
Aspirin-triggered Resolvin D1
Resolvins are a family of potent lipid mediators derived from both eicosapentaenoic acid and docosahexaenoic acid.
-
GC41227
17(R)-Resolvin D1 methyl ester
AspirintriggeredResolvin D1 methyl ester, ATRvD1 methyl ester, 17epiResolvin D1 methyl ester, 17(R)RvD1 methyl ester
17(R)-Resolvin D1 (17(R)-RvD1) is an aspirin-triggered epimer of RvD1 that reduces human polymorphonuclear leukocyte transendothelial migration, the earliest event in acute inflammation, with equipotency to RvD1 (EC50 = ~30 nM). -
GC45307
17(R)-Resolvin D3
Aspirin-triggered Resolvin D3, 17-epi-Resolvin D3, AT-RvD3, 17(R)-RvD3
-
GC41208
17(S)-HDHA
17(S)hydroxy Docosahexaenoic Acid, 17(S)HDoHE
17(S)-HDHA is a primary mono-oxygenation product of docosahexaenoic acid in human whole blood, human leukocytes, and mouse brain. -
GC46048
17(S)-HDHA-d5
17(S)-hydroxy Docosahexaenoic Acid-d5, 17(S)-HDoHE-d5
A neuropeptide with diverse biological activities -
GC40975
17(S)-HpDHA
17(S)hydroperoxy Docosahexaenoic Acid, 17(S)HpDoHE
17(S)-HpDHA is a mono-oxygenation product of docosahexaenoic acid in human whole blood, human leukocytes, human glial cells, and mouse brain. -
GC41160
1a,1b-dihomo Prostaglandin E2
1a,1b-dihomo PGE2
1a,1b-dihomo Prostaglandin E2 (PGE2) is a rare polyunsaturated fatty acid first identified in extracts of sheep vesicular gland microsomes, known to contain COX, incubated with adrenic acid. -
GC90803
2',3'-Dideoxyadenosine-5'-O-triphosphate (sodium salt)
A reverse transcriptase inhibitor and an active metabolite of ddA and ddI
-
GC42080
2'2'-cGAMP (sodium salt)
Adenosine-Guanosine 2’,2’-cyclic monophosphate, cGAMP(2’-5’), 2’,2’-Cyclic GMP-AMP
2'2'-cGAMP is a synthetic dinucleotide (CDN) that contains non-canonical 2'5'-phosphodiester bonds. -
GC42123
2-Aminopurine (hydrochloride)
2-AP
2-Aminopurine (hydrochloride) is a fluorescent analog of guanosine. -
GC42135
2-chloro Palmitic Acid
2-ClHA, 2-CLPA
2-chloro Palmitic Acid, an inflammatory lipid mediator, interferes with protein palmitoylation,induces ER-stress markers, reduced the ER ATP content, and activates transcription and secretion of IL-6 as well as IL-8.2-chloro Palmitic Acid disrupts the mitochondrial membrane potential and induces procaspase-3 and PARP cleavage.2-chloro Palmitic Acid can across blood-brain barrier (BBB) and compromises ER- and mitochondrial functions in the human brain endothelial cell line hCMEC/D3. -
GC42136
2-chloro Stearic Acid
α-Chlorostearic acid
2-chloro Stearic acid is a bioactive fatty acid that accumulates in primary human monocytes and neutrophils as well as murine neutrophils stimulated with phorbol 12-myristate 13-acetate. -
GC42082
20-carboxy Leukotriene B4
20carboxy LTB4
20-carboxy LTB4 is a metabolite of LTB4 in human neutrophils. -
GC41421
20-hydroxy Leukotriene B4
20hydroxy LTB4
20-hydroxy LTB4 is a metabolite of LTB4 in human neutrophils. -
GC40571
24(S),25-epoxy Cholesterol
24(S)-24,25-EC
24(S),25-epoxy Cholesterol is an oxysterol and the most abundant oxysterol in mouse ventral midbrain.
-
GC48482
28-Acetylbetulin
28-acetoxy Betulin, 28-O-Acetylbetulin, C-28-Acetylbetulin
A lupane triterpenoid with anti-inflammatory and anticancer activities -
GC49122
3′-deoxy Thymidine
2’,3’-Dideoxythymidine, d2T, ddThd
An antiviral nucleoside analog -
GC42242
3'-sulfo Galactosylsphingosine (ammonium salt)
Lyso 3’-sulfo Galactosylceramide, Lyso-Sulfatide, Sphingosine-1-Galactoside-3-Sulfate, Sulfogalactosylsphingosine
3'-sulfo Galactosylsphingosine is a form of sulfatide that is lacking the fatty acyl group. -
GC46583
3-Amino-2,6-Piperidinedione
α-Aminoglutarimide, 3-Aminoglutarimide, Glutamimide
An active metabolite of (±)-thalidomide -
GC42251
3-Bromotyrosine (trifluoroacetate salt)
3-bromo-Tyr
3-Bromotyrosine is a product of protein oxidation found after activation of eosinophils during an allergic response. -
GC42252
3-Bromotyrosine-13C9,15N (trifluoroacetate salt)
3-bromo-Tyr-13C9,15N
3-Bromotyrosine-13C9,15N is intended for use as an internal standard for the quantification of 3-bromotyrosine by GC- or LC-MS. -
GC45354
4β-Hydroxywithanolide E
NSC 212509
A withanolide with anti-inflammatory and anticancer activities -
GC45931
4(S),11(R)-DiHDoHE
A neuropeptide with diverse biological activities
-
GC91680
4-Acetamido Antipyrine
4-AAAP,NSC 331807
4-Acetamido antipyrine (4-AAAP) is an active metabolite of the non-opioid analgesic and antipyretic prodrug metamizole . -
GC42338
4-Aminobenzoic Acid hydrazide
4ABAH, Myeloperoxidase Inhibitor 1, NSC 640
4-Aminobenzoic Acid hydrazide is an irreversible MPO myeloperoxidase inhibitor with an IC50 of 0.3 μM. -
GC46630
4-CPPC
A MIF-2 inhibitor
-
GC42369
4-Deoxypyridoxine (hydrochloride)
4-Deoxypyridoxine, DOP, 4-DPD
4-Deoxypyridoxine (4-DPD) is a vitamin B6 antimetabolite with diverse biological activities. -
GC42374
4-epi-Chlortetracycline (hydrochloride)
7-chloro-2-Naphthacenecarboxamide
Chlortetracycline is an analog of tetracycline, a broad spectrum antibiotic. -
GA20418
4-Hydroxy-hippuric acid
p-Hydroxyhippuric Acid; para-Hydroxyhippuric Acid
Polyphenol metabolite. -
GC92085
4-O10b1
4-O10b1 is an ionizable cationic lipid (pKa = 5.148) that has been used in the generation of lipid nanoparticles (LNPs) for the delivery of siRNA in vitro and in vivo.
-
GC46673
4-octynyl Itaconate
ITalk
4-octynyl Itaconate (ITalk) is a specific bioorthogonal probe for quantitative and site-specific chemoproteomic profiling of Itaconation in living cells. -
GC48381
5'-pApA (sodium salt)
c-di-AMP Control, Cyclic di-AMP Negative Control
A linearized form of cyclic di-AMP -
GC48375
5'-pGpG (sodium salt)
c-di-GMP Control, Cyclic di-GMP Negative Control
A linearized form of cyclic di-GMP -
GC41126
5(S),12(S)-DiHETE
5(S),12(S)-DiHETE is a natural bioactive lipid derived from arachidonic acid.