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Home >> Signaling Pathways >> Membrane Transporter/Ion Channel

Membrane Transporter/Ion Channel

Products for  Membrane Transporter/Ion Channel

  1. Cat.No. Product Name Information
  2. GC34998 (S)-(-)-5-Fluorowillardiine hydrochloride

    (5S)-Fluorowillardiine hydrochloride; (S)-5-Fluorowillardiine hydrochloride

     (S)-(-)-5-Fluorowillardiine hydrochloride is a potent and specific AMPAR agonist. (S)-(-)-5-Fluorowillardiine hydrochloride Chemical Structure
  3. GC15768 (S)-(-)-5-Iodowillardiine hGluR5 kainate receptor agonist (S)-(-)-5-Iodowillardiine Chemical Structure
  4. GC14229 (S)-(-)-Bay K 8644 L-type Ca2+-channel activator (S)-(-)-Bay K 8644 Chemical Structure
  5. GC63321 (S)-(-)-Felodipine-d5 (S)-(-)-Felodipine-d5 Chemical Structure
  6. GC10370 (S)-(-)-HA-966 NMDA receptor antagonist (S)-(-)-HA-966 Chemical Structure
  7. GC64735 (S)-(-)-Levamisole (S)-(-)-Levamisole (Levamisole), an anthelmintic agent with immunomodulatory properties. (S)-(-)-Levamisole Chemical Structure
  8. GC41557 (S)-3'-amino Blebbistatin

    (-)-3'-amino Blebbistatin, m-amino Blebbistatin, meta-amino Blebbistatin

     (S)-3'-amino Blebbistatin is a more stable and less phototoxic form of (-)-blebbistatin, which is a selective cell-permeable inhibitor of non-muscle myosin II ATPases. (S)-3'-amino Blebbistatin Chemical Structure
  9. GC41484 (S)-3'-hydroxy Blebbistatin

    (-)-3'-hydroxy Blebbistatin, meta-hydroxy-Blebbistatin, m-hydroxy-Blebbistatin

     (S)-3'-hydroxy Blebbistatin is a more stable and less phototoxic form of (-)-blebbistatin, which is a selective cell-permeable inhibitor of non-muscle myosin II ATPases. (S)-3'-hydroxy Blebbistatin Chemical Structure
  10. GC17213 (S)-AMPA

    L-AMPA

     AMPA agonist (S)-AMPA Chemical Structure
  11. GC17313 (S)-CPW 399 AMPA agonist,subtype-selective,weakly desensitizing (S)-CPW 399 Chemical Structure
  12. GC41091 (S)-Lansoprazole

    (-)-Lansoprazole

     (S)-Lansoprazole is a proton pump inhibitor that irreversibly inhibits H+/K+-stimulated ATPase pumps in parietal cells (IC50 = 5.2 μM), inhibiting gastric acid secretion and increasing intragastric pH. (S)-Lansoprazole Chemical Structure
  13. GC60418 (S)-Lercanidipine hydrochloride (S)-Lercanidipine hydrochloride is the S-enantiomer of Lercanidipine hydrochloride. (S)-Lercanidipine hydrochloride Chemical Structure
  14. GC68476 (S)-Nicardipine

    (S)-YC-93 free base

     (S)-Nicardipine Chemical Structure
  15. GC41739 (S)-nitro-Blebbistatin

    S(-)7Desmethyl8nitro Blebbistatin

     (S)-nitro-Blebbistatin is a more stable form of (-)-blebbistatin, which is a selective cell-permeable inhibitor of non-muscle myosin II ATPases. (S)-nitro-Blebbistatin Chemical Structure
  16. GC15464 (S)-SNAP 5114 GABA uptake inhibitor (S)-SNAP 5114 Chemical Structure
  17. GC60423 (S)-UFR2709 hydrochloride (S)-UFR2709 (hydrochloride) is a competitive nAChR antagonist?and displays higher affinity for α4β2 nAChRs than for α7 nAChRs. (S)-UFR2709 hydrochloride Chemical Structure
  18. GC60425 (S)-Verapamil D7 hydrochloride

    (S)-(-)-Verapamil D7 hydrochloride

     (S)-Verapamil D7 hydrochloride ((S)-(-)-Verapamil D7 hydrochloride) is a deuterium labeled (S)-Verapamil hydrochloride. (S)-Verapamil hydrochloride (S(-)-Verapamil hydrochloride) inhibits leukotriene C4 (LTC4) and calcein transport by MRP1. (S)-Verapamil hydrochloride leads to the death of potentially resistant tumor cells. (S)-Verapamil D7 hydrochloride Chemical Structure
  19. GC60008 (S)-Verapamil hydrochloride (S)-Verapamil hydrochloride (S(-)-Verapamil hydrochloride) inhibits leukotriene C4 (LTC4) and calcein transport by MRP1. (S)-Verapamil hydrochloride leads to the death of potentially resistant tumor cells. (S)-Verapamil hydrochloride Chemical Structure
  20. GC69979 (S)-VQW-765

    (S)-AQW-051

    (S)-VQW-765 ((S)-AQW-051) is a partial agonist of the α7 nicotinic acetylcholine receptor (nAChR) with oral activity, selectivity and efficacy. It has potential applications in cognitive impairments associated with neurological diseases such as Alzheimer's disease or schizophrenia.

     (S)-VQW-765 Chemical Structure
  21. GC30212 (S)-Willardiine ((-)-Willardiine) (S)-Willardiine ((-)-Willardiine) is a potent agonist of AMPA/kainate receptors with EC50 of 44.8 uM. (S)-Willardiine ((-)-Willardiine) Chemical Structure
  22. GC35010 (Z)-Capsaicin (Z)-Capsaicin is the cis isomer of capsaicin, acts as an orally active TRPV1 agonist, and is used in the research of neuropathic pain. (Z)-Capsaicin Chemical Structure
  23. GC12927 (±)-Baclofen A GABAB agonist (±)-Baclofen Chemical Structure
  24. GC18603 (±)-Methoxyverapamil (hydrochloride)

    Gallopamil, NSC 274966

     (±)-Methoxyverapamil (hydrochloride) (Methoxyverapamil hydrochloride), a methoxy derivative of Verapamil, is a phenylalkylamine calcium antagonist. (±)-Methoxyverapamil (hydrochloride) Chemical Structure
  25. GC46366 1,2,3,4-Tetrahydro-β-carboline

    Tetrahydronorharman, Tetrahydro-β-carboline, THBC, Tryptoline

     A serotonin reuptake inhibitor and metabolite of tryptamine 1,2,3,4-Tetrahydro-β-carboline Chemical Structure
  26. GC61898 1,2,4-Trihydroxybenzene 1,2,4-Trihydroxybenzene (Hydroxyhydroquinone), a by-product of coffee bean roasting, increases intracellular Ca2+ concentration in rat thymic lymphocytes. 1,2,4-Trihydroxybenzene Chemical Structure
  27. GC45980 1,3-Dipalmitoyl-2-Octanoyl-rac-glycerol

    1,3-Dipalmitin-2-Octanoin, TG(16:0/8:0/16:0)

     A triacylglycerol 1,3-Dipalmitoyl-2-Octanoyl-rac-glycerol Chemical Structure
  28. GC38726 1,4-Cineole 1,4-Cineole is a widely distributed, natural, oxygenated monoterpene. 1,4-Cineole Chemical Structure
  29. GC49346 1-(3-Chlorophenyl)biguanide (hydrochloride)

    m-Chlorophenylbiguanide hydrochloride, meta-Chlorophenylbiguanide, m-CPBG, meta-CPBG

     A 5-HT3 receptor agonist 1-(3-Chlorophenyl)biguanide (hydrochloride) Chemical Structure
  30. GC12863 1-BCP

    Piperonylic acid piperidide

     potentiator of AMPA-mediated responses 1-BCP Chemical Structure
  31. GC41990 1-Decanoyl-rac-glycerol

    MG(10:0/0:0/0:0), 1-Monocaprin, 1-Monodecanoin

     1-Decanoyl-rac-glycerol is a monoacylglycerol that contains decanoic acid at the sn-1 position. 1-Decanoyl-rac-glycerol Chemical Structure
  32. GC16717 1-EBIO

    1Ethylbenzimidazolinone

     Activator of epithelial KCa channels 1-EBIO Chemical Structure
  33. GC39470 1-Octanol 1-Octanol (Octanol), a saturated fatty alcohol, is a T-type calcium channels (T-channels) inhibitor with an IC50 of 4 μM for native T-currents. 1-Octanol Chemical Structure
  34. GC49820 10,11-dihydro-10,11-dihydroxy Carbamazepine

    10,11-dihydro-10,11-dihydroxy CBZ, CBZ-diol, Dihydroxycarbazepine, Dihydroxycarbamazepine

     A metabolite of carbamazepine and oxcarbazepine 10,11-dihydro-10,11-dihydroxy Carbamazepine Chemical Structure
  35. GC13863 10Panx

    10Panx

     A peptide inhibitor of PANX1 10Panx Chemical Structure
  36. GC46047 14-Anhydrodigitoxigenin A cardenolide 14-Anhydrodigitoxigenin Chemical Structure
  37. GC40453 16(R)-HETE

    16(R)-Hydroxyeicosatetraenoic Acid

    Electrolyte and fluid transport in the kidney are regulated in part by arachidonic acid and its metabolites.

     16(R)-HETE Chemical Structure
  38. GC40454 16(S)-HETE

    16(S)-Hydroxyeicosatetraenoic Acid

     Electrolyte and fluid transport in the kidney are regulated in part by arachidonic acid and its metabolites. 16(S)-HETE Chemical Structure
  39. GC40455 17(R)-HETE

    17(R)-Hydroxyeicosatetraenoic Acid

     Electrolyte and fluid transport in the kidney are regulated in part by arachidonic acid and its metabolites. 17(R)-HETE Chemical Structure
  40. GC40456 17(S)-HETE

    17(S)-Hydroxyeicosatetraenoic Acid

     Electrolyte and fluid transport in the kidney are regulated in part by arachidonic acid and its metabolites. 17(S)-HETE Chemical Structure
  41. GC17223 17-PA GABAA receptor antagonist 17-PA Chemical Structure
  42. GC46464 17R(18S)-EpETE

    17R,18S-EEQ, 17R,18S-epoxy Eicosatetraenoic Acid

     An EPA metabolite and activator of BKCa channels 17R(18S)-EpETE Chemical Structure
  43. GC70652 2'MeO6MF 2'MeO6MF is a brain-penetrant positive allosteric modulator at α2β1γ2L and all α1-containing GABAA receptors. 2'MeO6MF Chemical Structure
  44. GC60455 2,2,2-Trichloroethanol 2,2,2-Trichloroethanol, the active form of Chloral hydrate, is an agonist for the nonclassical K2P channels TREK-1 (KCNK2) and TRAAK (KCNK4). 2,2,2-Trichloroethanol Chemical Structure
  45. GC12469 2,3-Butanedione-2-monoxime

    BDM|Diacetyl Monoxime|NSC 660|NSC 116103

     2,3-Butanedione-2-monoxime (Diacetyl monoxime), a myosin ATPase inhibitor, is a skeletal and cardiac muscle contraction inhibitor. 2,3-Butanedione-2-monoxime Chemical Structure
  46. GC17562 2-APB

    2-Aminoethoxydiphenyl borate, 2-APB, NSC 17107

     2-APB is a nonspecific antagonist of calcium channels, commonly used in studies of calcium signaling, such as in apoptosis, muscle contraction, and neural transmission. 2-APB Chemical Structure
  47. GC49718 2-Chloroadenosine 5-triphosphate (sodium salt)

    2-chloro ATP

     An adenine nucleotide and ATP analog 2-Chloroadenosine 5-triphosphate (sodium salt) Chemical Structure
  48. GC11267 2-Hydroxysaclofen GABAB receptor antagonist 2-Hydroxysaclofen Chemical Structure
  49. GC15416 2-Methylthioadenosine triphosphate tetrasodium salt 2-Methylthioadenosine triphosphate tetrasodium salt is a non-specific P2-receptor agonist. 2-Methylthioadenosine triphosphate tetrasodium salt Chemical Structure
  50. GC40377 20-HEPE 20-HEPE is a metabolite of eicosapentaenoic acid that is formed via ω-oxidation of EPA by cytochrome P450 (CYP) ω-oxidases, including human CYP4F3B. 20-HEPE Chemical Structure
  51. GC35075 20-HETE

    20-hydroxy Arachidonic Acid, 20-Hydroxyeicosatetraenoic Acid

     A quantitative analytical standard guaranteed to meet MaxSpec® identity, purity, stability, and concentration specifications 20-HETE Chemical Structure
  52. GC33673 24-Hydroxycholesterol 24-Hydroxycholesterol is a natural sterol, which serves as a positive allosteric modulator of N-Methyl-d-Aspartate (NMDA) receptorsR, and a potent activator of the transcription factors LXR. 24-Hydroxycholesterol Chemical Structure
  53. GC48395 3,3',5-Triiodo-L-thyronine (sodium salt hydrate)

    Liothyronine, T3, L3,3',5Triiodothyronine

     3,3',5-Triiodo-L-thyronine (sodium salt hydrate) is an active form of thyroid hormone. 3,3',5-Triiodo-L-thyronine (sodium salt hydrate) Chemical Structure
  54. GC33703 3,4,5-Trimethoxycinnamic acid 3,4,5-Trimethoxycinnamic acid is a phenylpropanoid isolated from the roots of Polygala tenuifoliaWILLD, with anti-stress effect, prolonging the sleeping time in animals. 3,4,5-Trimethoxycinnamic acid Chemical Structure
  55. GC11757 3-Bromocytisine

    3-Br-cytisine

     α4β4, α4β2 and α7 nACh receptor agonist 3-Bromocytisine Chemical Structure
  56. GC35108 3-Deoxyaconitine 3-Deoxyaconitine a diterpenoid alkaloid, is a sodium channel activator. 3-Deoxyaconitine Chemical Structure
  57. GC12506 3-Methyl-GABA GABA aminotransferase activator 3-Methyl-GABA Chemical Structure
  58. GC70850 4′-Demethylnobiletin 4′-Demethylnobiletin is a bioactive metabolite that activates the PKA/ERK/CREB signaling pathway, enhances CRE-mediated transcription in hippocampal neurons, and reverses memory impairment associated with NMDA receptor antagonism by stimulating ERK signaling. 4′-Demethylnobiletin Chemical Structure
  59. GC42475 4α-Phorbol 12,13-didecanoate

    4α-PDD, 4α-Phorbol 12,13-dicaprinate

     4α-Phorbol 12,13-didecanoate is a negative control for phorbol esters, phorbol 12-myristate 13-acetate and phorbol 12,13-didecanoate (PDD). 4α-Phorbol 12,13-didecanoate Chemical Structure
  60. GC49252 4’-hydroxy Trazodone A metabolite of trazodone 4’-hydroxy Trazodone Chemical Structure
  61. GC17675 4,4-Pentamethylenepiperidine hydrochloride M2 proton channel blocker 4,4-Pentamethylenepiperidine hydrochloride Chemical Structure
  62. GC42327 4,9-Anhydrotetrodotoxin

    4,9-anhydro-TTX

    4,9-Anhydrotetrodotoxin (4,9-anhydro-TTX) is a derivative of TTX that selectively blocks inward sodium current through Nav1.6 voltage-activated sodium channels (IC50 = 7.8 nM in Xenopus oocytes).

     4,9-Anhydrotetrodotoxin Chemical Structure
  63. GC68080 4-(Phenyldiazenyl)benzoic acid 4-(Phenyldiazenyl)benzoic acid Chemical Structure
  64. GC33504 4-Acetamidobutanoic acid (N-acetyl GABA)

    4-Acetamidobutanoic Acid, N-acetyl-4-Aminobutanoic Acid, N-acetyl-γ-Aminobutyric Acid, NSC 27423

     4-Acetamidobutanoic acid (N-acetyl GABA) (N-acetyl GABA), the main metabolite of GABA, exhibits antioxidant and antibacterial activities. 4-Acetamidobutanoic acid (N-acetyl GABA) Chemical Structure
  65. GC17469 4-Aminopyridine

    4-AP, BRL 34915, Dalfampridine, Fampridine, NSC 15041

     potassium channel-blocking agent 4-Aminopyridine Chemical Structure
  66. GC42346 4-bromo A23187

    4-Bromocalcimycin

    4-bromo A23187 is a halogenated analog of the highly selective calcium ionophore A23187.

     4-bromo A23187 Chemical Structure
  67. GC49575 4-hydroxy Omeprazole sulfide

    4-hydroxy OMEP sulfide, 4-hydroxy OMP sulfide, 4-hydroxy OMZ sulfide

     A metabolite of omeprazole 4-hydroxy Omeprazole sulfide Chemical Structure
  68. GC42414 4-hydroxy Tolbutamide 4-hydroxy Tolbutamide is a cytochrome P450 2C8 (CYP2C8) and CYP2C9 metabolite of tolbutamide, a first-generation potassium channel blocker. 4-hydroxy Tolbutamide Chemical Structure
  69. GA20418 4-Hydroxy-hippuric acid

    p-Hydroxyhippuric Acid; para-Hydroxyhippuric Acid

     Polyphenol metabolite. 4-Hydroxy-hippuric acid Chemical Structure
  70. GC18631 4BP-TQS An agonist of α7 subunit-containing nAChRs 4BP-TQS Chemical Structure
  71. GC16801 5'-Iodoresiniferatoxin TRPV1 (VR1) receptor antagonist 5'-Iodoresiniferatoxin Chemical Structure
  72. GC48843 5α-Androst-16-en-3α-ol

    Androstenol, E 281, NSC 71076

     A pheromone with diverse biological activities 5α-Androst-16-en-3α-ol Chemical Structure
  73. GC49326 5β-Dihydroprogesterone

    5β-DHP, NSC 82868, 5β-Pregnanedione

     A progesterone receptor agonist and metabolite of progesterone 5β-Dihydroprogesterone Chemical Structure
  74. GC16799 5,7-Dichlorokynurenic acid

    5,7-DCKA, DCKA

     NMDA receptor antagonist 5,7-Dichlorokynurenic acid Chemical Structure
  75. GC14598 5,7-Dichlorokynurenic acid sodium salt NMDA receptor antagonist 5,7-Dichlorokynurenic acid sodium salt Chemical Structure
  76. GC10898 5-(N,N-dimethyl)-Amiloride (hydrochloride)

    DMA,L-591,605,MK-685

     NHE1, NHE2, and NHE3 inhibitor 5-(N,N-dimethyl)-Amiloride (hydrochloride) Chemical Structure
  77. GC35147 5-(N,N-Hexamethylene)-amiloride

    HMA

     An amiloride derivative with diverse biological activities 5-(N,N-Hexamethylene)-amiloride Chemical Structure
  78. GC60026 5-AAM-2-CP 5-AAM-2-CP is a major metabolite of Acetamiprid. 5-AAM-2-CP Chemical Structure
  79. GC60027 5-AMAM-2-CP 5-AMAM-2-CP is a major metabolite of Acetamiprid. 5-AMAM-2-CP Chemical Structure
  80. GC13943 5-BDBD P2X4 receptor antagonist 5-BDBD Chemical Structure
  81. GC60029 5-Hydroxydecanoate sodium 5-Hydroxydecanoate sodium is a selective ATP-sensitive K+ (KATP) channel blocker (IC50 of ~30 μM). 5-Hydroxydecanoate sodium Chemical Structure
  82. GC60530 5-Hydroxylansoprazole 5-Hydroxylansoprazole (AG1908) is an active metabolite of Lansoprazole in plasma. 5-Hydroxylansoprazole Chemical Structure
  83. GC50179 5J 4 CRAC channel blocker; anti-inflammatory 5J 4 Chemical Structure
  84. GC18176 5α,6β-Dihydroxycholestanol

    Cholestanetriol, NSC 124751, NSC 18178, 5α,6β-di-OHC

     5α,6β-Dihydroxycholestanol is an oxysterol metabolite of cholesterol formed from conversion of cholesterol epoxides by 5,6-epoxysterol hydrolase. 5α,6β-Dihydroxycholestanol Chemical Structure
  85. GC10188 6'-Iodoresiniferatoxin TRPV1 (VR1) vanilloid receptor partial agonist 6'-Iodoresiniferatoxin Chemical Structure
  86. GC30943 6,2'-Dihydroxyflavone 6,2'-Dihydroxyflavone is a novel antagonist of GABAA receptor. 6,2'-Dihydroxyflavone Chemical Structure
  87. GC11284 6-(4-Methoxyphenyl)-3-pyridazinamine GABAA receptor antagonist 6-(4-Methoxyphenyl)-3-pyridazinamine Chemical Structure
  88. GC65593 6-Benzoylheteratisine 6-Benzoylheteratisine is a naturally occurring antagonist of the Na+ channel activator aconitine. 6-Benzoylheteratisine Chemical Structure
  89. GC13679 6-Iodonordihydrocapsaicin Vanilloid receptor antagonist 6-Iodonordihydrocapsaicin Chemical Structure
  90. GC31309 6-Methoxy-2-naphthoic acid (Naproxen impurity O)

    6-methoxy Naphthalene Acetic Acid, 6-methoxy-2-Naphthylacetic Acid, 6-MNA, NSC 408786

     6-Methoxy-2-naphthoic acid (Naproxen impurity O) is an NMDA receptor modulator extracted from patent WO 2012019106 A2. 6-Methoxy-2-naphthoic acid (Naproxen impurity O) Chemical Structure
  91. GC30898 6-Methylflavone 6-Methylflavone is an activator of α1β2γ2L and α1β2 GABAA receptors. 6-Methylflavone Chemical Structure
  92. GC10781 7-Chlorokynurenic acid

    7-CKA, 7-CTKA, 7-chloro KYNA, NSC 149792

     NMDA receptor glycine site antagonist 7-Chlorokynurenic acid Chemical Structure
  93. GC11395 7-Chlorokynurenic acid sodium salt NMDA receptor antagonist acting at the glycine site 7-Chlorokynurenic acid sodium salt Chemical Structure
  94. GC13691 7ACC1

    Coumarin D 1421, 7-DCCA, 7-Diethylamino-2-oxo-2H-chromen-3-carboxylic Acid

     MCT inhibitor 7ACC1 Chemical Structure
  95. GC14642 7ACC2 MCT inhibitor 7ACC2 Chemical Structure
  96. GC70705 8-Azido-ATP trisodium 8-Azido-ATP (8-N3-ATP) trisodium, a photoreactable nucleotide analog, is useful for the identification of proteins, such as DNA-dependent RNA polymerase. 8-Azido-ATP trisodium Chemical Structure
  97. GC10119 8-Bromo-cGMP, sodium salt

    ​​8-bromo-cGMP, 8-bromo Guanosine 3’,5’-cyclic monophosphate

     8-Bromo-cGMP is a cell-permeable cGMP analog that induces PKG activation. 8-Bromo-cGMP, sodium salt Chemical Structure
  98. GC42621 8-bromo-Cyclic ADP-Ribose (sodium salt)

    8-bromo-cADPR, 8-bromo-cADP-Ribose

     Cyclic ADP-ribose (cADP-ribose) is a calcium mobilizing nucleotide that is biosynthesized from NAD+ by cADP-ribose synthases, including CD38. 8-bromo-Cyclic ADP-Ribose (sodium salt) Chemical Structure
  99. GC11483 8-CPT-2Me-cAMP, sodium salt

    8-CPT-2MecAMP, 8-pCPTcAMP, 8-pCPT-2′-OMe-cAMP

     8-CPT-2Me-cAMP, sodium salt is a selective activator of exchange proteins activated by cAMP (Epac), the cAMP sensitive guanine nucleotide exchange factors (GEFs) for the small GTPases Rap1 and Rap2. 8-CPT-2Me-cAMP, sodium salt Chemical Structure
  100. GC60542 8-Gingerol A natural TRPV1 agonist 8-Gingerol Chemical Structure
  101. GC49017 8-hydroxy Amoxapine A metabolite of amoxapine 8-hydroxy Amoxapine Chemical Structure

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