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Home >> Signaling Pathways >> Membrane Transporter/Ion Channel >> Calcium Channel

Calcium Channel

Calcium channel is an ion channel that selectively permeable to calcium ions. It serves vital functions in cellular signal transduction.

Products for  Calcium Channel

  1. Cat.No. Product Name Information
  2. GC15513 ω-Agatoxin IVA ω-Agatoxin IVA is a potent, selective P/Q type Ca2+ (Cav2.1) channel blocker with IC50s of 2 nM and 90 nM for P-type and Q-type Ca2+ channels, respectively. ω-Agatoxin IVA Chemical Structure
  3. GC12608 ω-Agatoxin TK ω-Agatoxin TK, a peptidyl toxin of the venom of Agelenopsis aperta, is a potent and selective P/Q type Ca2+ channel blocker. ω-Agatoxin TK Chemical Structure
  4. GC13886 ω-Conotoxin GVIA ω-Conotoxin GVIA is a cone snail toxin that selectively blocks N-type channels in neurons . ω-Conotoxin GVIA Chemical Structure
  5. GC18070 ω-Conotoxin MVIIC wide spectrum blocker of N, P and Q type calcium channels ω-Conotoxin MVIIC Chemical Structure
  6. GC31248 β-Amino Acid Imagabalin Hydrochloride (PD-0332334)

    PD-0332334

     β-Amino Acid Imagabalin Hydrochloride (PD-0332334) (PD-0332334) is a ligand for the α2δ subunit of the voltage-dependent calcium channel. β-Amino Acid Imagabalin Hydrochloride (PD-0332334) Chemical Structure
  7. GC70188 ω-Agatoxin IVA TFA

    ω-Agatoxin IVA TFA is an effective selective blocker of P/Q-type Ca2+ (Cav2.1) channels, with IC50 values of 2 nM and 90 nM for P-type and Q-type Ca2+ channels, respectively. ω-Agatoxin IVA TFA (IC50, 30-225 nM) inhibits high potassium-induced glutamate release and calcium influx. It also blocks the release of serotonin and adrenaline induced by high potassium, without affecting L-type or N-type calcium channels.

     ω-Agatoxin IVA TFA Chemical Structure
  8. GC45241 ω-Conotoxin GVIA (trifluoroacetate salt) ω-Conotoxin GVIA is a peptide originally isolated from the marine mollusk C. ω-Conotoxin GVIA (trifluoroacetate salt) Chemical Structure
  9. GA24016 ω-Conotoxin MVIIA ω-Conotoxin MVIIA (SNX-111), a peptide, is a potent and selective block of N-type calcium channels antagonist. ω-Conotoxin MVIIA Chemical Structure
  10. GC64899 ω-Conotoxin MVIIC TFA ω-Conotoxin MVIIC TFA Chemical Structure
  11. GN10612 (+)- Praeruptorin C (+)- Praeruptorin C Chemical Structure
  12. GC30933 (+)-Kavain

    Kawain, NSC 112162

    An Analytical Reference Standard

     (+)-Kavain Chemical Structure
  13. GC63940 (-)-Denudatin B (-)-Denudatin B is an antiplatelet agent. (-)-Denudatin B Chemical Structure
  14. GN10445 (-)-pareruptorin A (-)-pareruptorin A Chemical Structure
  15. GC14484 (-)-Xestospongin C

    XeC, Araguspongine E

    IP3-dependent Ca2+ release inhibitor

     (-)-Xestospongin C Chemical Structure
  16. GC50536 (2R/S)-6-PNG

    (±)-6-PN

     CaV3.2 blocker; active in vivo (2R/S)-6-PNG Chemical Structure
  17. GC13895 (R)-(+)-Bay K 8644

    NI 105, R 4407

     L-type Ca2+-channel blocker (R)-(+)-Bay K 8644 Chemical Structure
  18. GC66419 (R)-Lercanidipine-d3 hydrochloride (R)-lercanidipine D3 (hydrochloride) is a deuterium labeled (R)-Lercanidipine hydrochloride. (R)-Lercanidipine D3 (hydrochloride), the R-enantiomer of Lercanidipine, is a calcium channel blocker. (R)-Lercanidipine-d3 hydrochloride Chemical Structure
  19. GC68475 (R)-Nicardipine

    (R)-YC-93 free base

     (R)-Nicardipine Chemical Structure
  20. GC61873 (Rac)-MEM 1003 (Rac)-MEM 1003 is the racemate of MEM 1003. (Rac)-MEM 1003 Chemical Structure
  21. GC14229 (S)-(-)-Bay K 8644 L-type Ca2+-channel activator (S)-(-)-Bay K 8644 Chemical Structure
  22. GC63321 (S)-(-)-Felodipine-d5 (S)-(-)-Felodipine-d5 Chemical Structure
  23. GC60418 (S)-Lercanidipine hydrochloride (S)-Lercanidipine hydrochloride is the S-enantiomer of Lercanidipine hydrochloride. (S)-Lercanidipine hydrochloride Chemical Structure
  24. GC68476 (S)-Nicardipine

    (S)-YC-93 free base

     (S)-Nicardipine Chemical Structure
  25. GC60425 (S)-Verapamil D7 hydrochloride

    (S)-(-)-Verapamil D7 hydrochloride

     (S)-Verapamil D7 hydrochloride ((S)-(-)-Verapamil D7 hydrochloride) is a deuterium labeled (S)-Verapamil hydrochloride. (S)-Verapamil hydrochloride (S(-)-Verapamil hydrochloride) inhibits leukotriene C4 (LTC4) and calcein transport by MRP1. (S)-Verapamil hydrochloride leads to the death of potentially resistant tumor cells. (S)-Verapamil D7 hydrochloride Chemical Structure
  26. GC60008 (S)-Verapamil hydrochloride (S)-Verapamil hydrochloride (S(-)-Verapamil hydrochloride) inhibits leukotriene C4 (LTC4) and calcein transport by MRP1. (S)-Verapamil hydrochloride leads to the death of potentially resistant tumor cells. (S)-Verapamil hydrochloride Chemical Structure
  27. GC18603 (±)-Methoxyverapamil (hydrochloride)

    Gallopamil, NSC 274966

     (±)-Methoxyverapamil (hydrochloride) (Methoxyverapamil hydrochloride), a methoxy derivative of Verapamil, is a phenylalkylamine calcium antagonist. (±)-Methoxyverapamil (hydrochloride) Chemical Structure
  28. GC61898 1,2,4-Trihydroxybenzene 1,2,4-Trihydroxybenzene (Hydroxyhydroquinone), a by-product of coffee bean roasting, increases intracellular Ca2+ concentration in rat thymic lymphocytes. 1,2,4-Trihydroxybenzene Chemical Structure
  29. GC45980 1,3-Dipalmitoyl-2-Octanoyl-rac-glycerol

    1,3-Dipalmitin-2-Octanoin, TG(16:0/8:0/16:0)

     A triacylglycerol 1,3-Dipalmitoyl-2-Octanoyl-rac-glycerol Chemical Structure
  30. GC39470 1-Octanol 1-Octanol (Octanol), a saturated fatty alcohol, is a T-type calcium channels (T-channels) inhibitor with an IC50 of 4 μM for native T-currents. 1-Octanol Chemical Structure
  31. GC74657 1-Octanol-d17

    Octanol-d17

     1-Octanol-d17 is the deuterium labeled 1-Octanol. 1-Octanol-d17 Chemical Structure
  32. GC49820 10,11-dihydro-10,11-dihydroxy Carbamazepine

    10,11-dihydro-10,11-dihydroxy CBZ, CBZ-diol, Dihydroxycarbazepine, Dihydroxycarbamazepine

     A metabolite of carbamazepine and oxcarbazepine 10,11-dihydro-10,11-dihydroxy Carbamazepine Chemical Structure
  33. GC90815 2',3'-cyclic NADP+ (sodium salt)

    A substrate for CNP

     2',3'-cyclic NADP+ (sodium salt) Chemical Structure
  34. GC17562 2-APB

    2-Aminoethoxydiphenyl borate, 2-APB, NSC 17107

     2-APB is a nonspecific antagonist of calcium channels, commonly used in studies of calcium signaling, such as in apoptosis, muscle contraction, and neural transmission. 2-APB Chemical Structure
  35. GC42475 4α-Phorbol 12,13-didecanoate

    4α-PDD, 4α-Phorbol 12,13-dicaprinate

     4α-Phorbol 12,13-didecanoate is a negative control for phorbol esters, phorbol 12-myristate 13-acetate and phorbol 12,13-didecanoate (PDD). 4α-Phorbol 12,13-didecanoate Chemical Structure
  36. GC42346 4-bromo A23187

    4-Bromocalcimycin

    4-bromo A23187 is a halogenated analog of the highly selective calcium ionophore A23187.

     4-bromo A23187 Chemical Structure
  37. GC90867 8-bromo NAD+ (sodium salt)

    A prodrug form of 8-bromo-cADPR

     8-bromo NAD+ (sodium salt) Chemical Structure
  38. GC10119 8-Bromo-cGMP, sodium salt

    ​​8-bromo-cGMP, 8-bromo Guanosine 3’,5’-cyclic monophosphate

     8-Bromo-cGMP is a cell-permeable cGMP analog that induces PKG activation. 8-Bromo-cGMP, sodium salt Chemical Structure
  39. GC42621 8-bromo-Cyclic ADP-Ribose (sodium salt)

    8-bromo-cADPR, 8-bromo-cADP-Ribose

     Cyclic ADP-ribose (cADP-ribose) is a calcium mobilizing nucleotide that is biosynthesized from NAD+ by cADP-ribose synthases, including CD38. 8-bromo-Cyclic ADP-Ribose (sodium salt) Chemical Structure
  40. GC11178 A-7 hydrochloride calmodulin antagonist A-7 hydrochloride Chemical Structure
  41. GC11200 A23187

    Calcimycin

    A23187, free acid is a Ca2+ ionophore

     A23187 Chemical Structure
  42. GC19016 ABT-639 ABT-639 is a novel, peripherally acting, selective T-type Ca2+ channel blocker. ABT-639 Chemical Structure
  43. GC33720 ABT-639 hydrochloride ABT-639 hydrochloride is a novel, peripherally acting, selective T-type Ca2+ channel blocker. ABT-639 hydrochloride Chemical Structure
  44. GC14142 Acetylcholine Chloride

    ACh

     Major transmitter at many nervous sites Acetylcholine Chloride Chemical Structure
  45. GC31100 ACT-709478

    ACT-709478

     ACT-709478 is a potent, selective, orally active, and brain penetrating T-type calcium channel blocker. ACT-709478 Chemical Structure
  46. GC32672 AE0047 Hydrochloride AE0047 Hydrochloride is a calcium blocker, used in the research of hypertensive disease. AE0047 Hydrochloride Chemical Structure
  47. GC18274 Amiprofos-methyl

    APM, NSC 313446

     Amiprofos-methyl (APM) is a phosphoric amide herbicide. Amiprofos-methyl Chemical Structure
  48. GC13523 Amlodipine

    Intervask, Pelmec

     Calcium channel blocker Amlodipine Chemical Structure
  49. GC13146 Amlodipine Besylate Block of L-type calcium channel Amlodipine Besylate Chemical Structure
  50. GC35325 Amlodipine maleate Amlodipine maleate is a dihydropyridine calcium channel blocker, acts as an orally active antianginal agent. Amlodipine maleate Chemical Structure
  51. GC32566 Anipamil Anipamil is a long-acting calcium channel blocker, used for the treatment of cardiovascular disease. Anipamil Chemical Structure
  52. GC34049 Aranidipine (MPC1304) Aranidipine (MPC1304) (MPC1304) is a Ca2+ channel antagonist with potent and long-lasting antihypertensive effects. Aranidipine (MPC1304) Chemical Structure
  53. GC42876 Autocamtide 2 (trifluoroacetate salt) Autocamtide 2 is a peptide substrate for calcium/calmodulin-dependent protein kinase (CaMK) and CaMKII. Autocamtide 2 (trifluoroacetate salt) Chemical Structure
  54. GC15099 Autocamtide-2-related inhibitory peptide inhibitor of calmodulin-dependent protein kinase II (CaM-kinase II, CaMKII) Autocamtide-2-related inhibitory peptide Chemical Structure
  55. GC15101 Azelnidipine

    CS 905, RS 9054

     L-type calcium channel blocker;antihypertensive Azelnidipine Chemical Structure
  56. GC35451 Azelnidipine D7 Azelnidipine D7 Chemical Structure
  57. GC61493 Azumolene Azumolene (EU4093 free base), a Dantrolene analog, is a muscle relaxant. Azumolene Chemical Structure
  58. GC42893 Azumolene (sodium salt)

    EU4093

     Azumolene is a muscle relaxant that inhibits the release of calcium from skeletal muscle sarcoplasmic reticulum. Azumolene (sodium salt) Chemical Structure
  59. GC35469 Barnidipine Barnidipine (Mepirodipine) is an L-type calcium antagonist (CaA) with high affinity for [3H] initrendipine binding sites (Ki=0.21 nmol/l), has selective action against CaA receptors. Barnidipine Chemical Structure
  60. GC13289 Barnidipine (hydrochloride)

    YM 09730-5

     calcium-channel blocker Barnidipine (hydrochloride) Chemical Structure
  61. GC72475 BBT BBT is an enhancer of impaired glucose-stimulated insulin secretion (GSIS). BBT Chemical Structure
  62. GC13888 Benidipine HCl

    (±)-Benidipine, KW-3049

     Benidipine HCl is a dihydropyridine calcium channel blocker for the treatment of high blood pressure (hypertension). Benidipine HCl Chemical Structure
  63. GC15533 Bepridil hydrochloride Calcium channel blocker Bepridil hydrochloride Chemical Structure
  64. GC39743 Bepridil hydrochloride hydrate Bepridil hydrochloride hydrate ((±)-Bepridil hydrochloride hydrate) is a non-selective, long-acting Ca+ channel antagonist and Na+, K+ channel inhibitor, with antianginal and type I antiarrhythmic effects. Bepridil hydrochloride hydrate Chemical Structure
  65. GC39546 Bevantolol hydrochloride

    CI-755, DL-Bevantolol, NC-1400

     A β1-AR antagonist Bevantolol hydrochloride Chemical Structure
  66. GC70402 BMS-192364 BMS-192364 is targeting the Gα-RGS interaction to produce an inactive Gα-RGS complex. BMS-192364 Chemical Structure
  67. GC42984 BTC (potassium salt) BTC (potassium salt) is a low affinity calcium indicator (Kd approximately 7-26 μM) featuring many desirable properties for cellular calcium imaging, including long excitation wavelengths (400/485 nm), low sensitivity to Mg2+, and accuracy of ratiometric measurement. BTC (potassium salt) Chemical Structure
  68. GC42985 BTC AM BTC AM is a cell-permeable acetoxy-methyl ester of BTC. BTC AM Chemical Structure
  69. GC50200 BX 430

    Blocker of P2X4 Compound 3.0

     Selective P2X4 allosteric antagonist BX 430 Chemical Structure
  70. GC30977 Ca2+ channel agonist 1 Ca2+ channel agonist 1 is an agonist of N-type Ca2+ channel and an inhibitor of Cdk2, with EC50s of 14.23 μM and 3.34 μM, respectively, and is used as a potential treatment for motor nerve terminal dysfunction. Ca2+ channel agonist 1 Chemical Structure
  71. GC43115 Cal Green™ 1 (potassium salt)

    Calcium Green-1

    Cal Green™ 1 is a cell-impermeant fluorescent calcium indicator that is characterized by high quantum yield and low phototoxicity.

     Cal Green™ 1 (potassium salt) Chemical Structure
  72. GC43116 Cal Green™ 1 AM

    Calcium Green-1 AM

     Cal Green™ 1 AM is a cell-permeant fluorescent calcium indicator (Excitation 506 nm; Emission 531 nm). Cal Green™ 1 AM Chemical Structure
  73. GC32616 Calcium channel-modulator-1 Calcium channel-modulator-1 is a calcium channel modulator; blocks aortic contraction with an IC50 of 0.8 μM. Calcium channel-modulator-1 Chemical Structure
  74. GC14326 Calmidazolium chloride

    R 24571

    Calmodulin antagonist

     Calmidazolium chloride Chemical Structure
  75. GC43128 Calmodulin-Dependent Protein Kinase II (290-309) (trifluoroacetate salt) Calmodulin-dependent protein kinase II (290-309) is a synthetic peptide derived from the rat brain protein sequence that contains the calmodulin binding domain. Calmodulin-Dependent Protein Kinase II (290-309) (trifluoroacetate salt) Chemical Structure
  76. GC12104 CALP1

    Calcium-like Peptide 1

    Cell-permeable calmodulin (CaM) agonist

     CALP1 Chemical Structure
  77. GC65081 CALP1 TFA CALP1 TFA is a calmodulin (CaM) agonist (Kd of 88 ?M) with binding to the CaM EF-hand/Ca2+-binding site. CALP1 TFA Chemical Structure
  78. GC14889 CALP2 Cell-permeable calmodulin (CaM) antagonist CALP2 Chemical Structure
  79. GC61508 CALP2 TFA CALP2 TFA is a calmodulin (CaM) antagonist (Kd of 7.9 ?M) with high affinity for binding to the CaM EF-hand/Ca2+-binding site. CALP2 TFA Chemical Structure
  80. GC17687 CALP3 Cell-permeable calmodulin (CaM) agonist CALP3 Chemical Structure
  81. GC15930 Camstatin analog of PEP-19 with antagonism of calmodulin Camstatin Chemical Structure
  82. GC39646 Carboxyamidotriazole Orotate

    L-651582 Orotate; CAI Orotate

     Carboxyamidotriazole Orotate (L-651582 Orotate) is the orotate salt form of Carboxyamidotriazole (CAI), an orally bioavailable signal transduction inhibitor. Carboxyamidotriazole Orotate Chemical Structure
  83. GN10791 Catharanthine Catharanthine Chemical Structure
  84. GN10715 Catharanthine Tartrate

    (+)3,4Didehydrocoronaridine

     Catharanthine Tartrate Chemical Structure
  85. GC35619 Cav 2.2 blocker 1 Cav 2.2 blocker 1 (compound 9) is a N-type calcium channel (Cav 2.2) blocker for the treatment of pain, with an IC50 of 1 nM. Cav 2.2 blocker 1 Chemical Structure
  86. GC65959 CaV1.3 antagonist-1 CaV1.3 antagonist-1 is a potent and highly selective CaV1.3 L-type calcium channel (LTCC) antagonist with an IC50 of 1.7 μM. CaV1.3 antagonist-1 inhibits CaV1.3 LTCC >600-fold more potently than CaV1.2 LTCC. CaV1.3 antagonist-1, a cyclopentyl derivative, has the potential for Parkinson's disease research. CaV1.3 antagonist-1 Chemical Structure
  87. GC31332 CDN1163 An allosteric activator of SERCA2 CDN1163 Chemical Structure
  88. GC16911 CGS 9343B

    KW-5617, Zaldaride Maleate

     CGS 9343B (CGS-9343B) is a potent, orally active and selective inhibitor of calmodulin. CGS 9343B Chemical Structure
  89. GC12312 Cilnidipine

    FRC 8653

     Blocker of Dual L- and N-type calcium channel Cilnidipine Chemical Structure
  90. GC11695 Cinnarizine antihistamine and calcium channel blocker Cinnarizine Chemical Structure
  91. GC60709 Cinnarizine D8 An internal standard for the quantification of cinnarizine Cinnarizine D8 Chemical Structure
  92. GC12095 cis-Ned 19 nicotinic acid adenine dinucleotide phosphate (NAADP) antagonist cis-Ned 19 Chemical Structure
  93. GC16128 Clevidipine Butyrate

    rac-Clevidipine

     Clevidipine Butyrate is a short-acting dihydropyridine calcium channel antagonist (IC50= 7.1 nM, V(H) = -40 mV ) under development for treatment of perioperative hypertension. Clevidipine Butyrate Chemical Structure
  94. GC74202 Coelenterazine h hydrochloride

    2-Deoxycoelenterazine hydrochloride; CLZN-h hydrochloride

     Coelenterazine h (2-Deoxycoelenterazine) drochloride, a coelenterazine derivative, is a luminescent substrate for RLuc8. Coelenterazine h hydrochloride Chemical Structure
  95. GC35738 CP-060 CP-?060 is a potent Ca2+ antagonist, inhibits Ca2+ overload and possesses antioxidant and cardioprotective activities. CP-060 Chemical Structure
  96. GC17690 Cromolyn sodium Mast cell membrane stabilizer Cromolyn sodium Chemical Structure
  97. GC31834 CV-159 CV-159 is a unique dihydropyridine Ca2+ antagonist with an anti-calmodulin (CaM) action, and has antiinflammatory activities. CV-159 Chemical Structure
  98. GC63967 Cycleanine

    O,O-Dimethylisochondrodendrine, O-Methylnorcycleanine

     Cycleanine is a potent vascular selective Calcium antagonist. Cycleanine Chemical Structure
  99. GC62179 Cyclic ADP-ribose Cyclic ADP-ribose (cADPR) is a potent second messenger for calcium mobilization that is synthesized from NAD+ by an ADP-ribosyl cyclase. Cyclic ADP-ribose Chemical Structure
  100. GC43338 Cyclic ADP-Ribose (ammonium salt)

    cADP-Ribose；cADPR

     Cyclic ADP-ribose (cADP-ribose) is an endogenous metabolite of NAD+ that mobilizes the release of stored Ca2+ in the endoplasmic reticulum via ryanodine receptors in various cell types. Cyclic ADP-Ribose (ammonium salt) Chemical Structure
  101. GC61792 Cyclic ADP-ribose ammonium

    cADPR ammonium

     Cyclic ADP-ribose ammonium Chemical Structure

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