NVP-2 |
Catalog No.GC34056 |
NVP-2 is a potent and selective ATP-competitive cyclin dependent kinase 9 (CDK9) probe, inhibits CDK9/CycT activity with an IC50 of 0.514 nM. NVP-2 displays inhibitory effcts on CDK1/CycB, CDK2/CycA and CDK16/CycY kinases with IC50 values of 0.584 ?M, 0.706 ?M, and 0.605 ?M, respectively. NVP-2 induces cell apoptosis.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 1263373-43-8
Sample solution is provided at 25 µL, 10mM.
NVP-2 is a CDK9 inhibitor with an IC50 of 0.5 nM.
[1]. Wang J, et al. SnapShot: Kinase Inhibitors I. Mol Cell. 2015 May 21;58(4):708.e1.
Average Rating: 5
(Based on Reviews and 30 reference(s) in Google Scholar.)GLPBIO products are for RESEARCH USE ONLY. Please make sure your review or question is research based.
Required fields are marked with *