SAICAR (hydrate) (Synonyms: Succino-AICAR, Succinyl-5-aminoimidazole-4-carboxamide-1-ribose-5'-phosphate) |
Catalog No.GC48505 |
An intermediate for purine synthesis
Products are for research use only. Not for human use. We do not sell to patients.
Sample solution is provided at 25 µL, 10mM.
SAICAR is an intermediate in the de novo purine nucleotide synthesis pathway. It is reported to stimulate pyruvate kinase isoform M2 and to promote cancer cell survival in conditions of limited glucose availability.1
1.Keller, K.E., Tan, I.S., and Lee, Y.S.SAICAR stimulates pyruvate kinase isoform M2 and promotes cancer cell survival in glucose-limited conditionsScience3381069-1072(2012)
Average Rating: 5
(Based on Reviews and 4 reference(s) in Google Scholar.)GLPBIO products are for RESEARCH USE ONLY. Please make sure your review or question is research based.
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