Salbutamol |
Catalog No.GC71682 |
Salbutamol (Albuterol) is a short-acting beta-2 adrenergic receptor agonist with oral activity.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 18559-94-9
Sample solution is provided at 25 µL, 10mM.
Salbutamol (16 μM, 24 h) significantly induces EMT, migration and invasion by ERK (extracellular signal-regulated kinase) phosphorylation in gastric cancer cells[1].
Salbutamol (5 mg/kg/day, orally, for 2 consecutive weeks) can increase tumor growth in nude mice with gastric cance[1].
Salbutamol (6 mg/kg orally for 4 weeks) has a significant protective effect against STZ -induced skeletal muscle atrophy in diabetic rats[2].
References:
[1]. Lu Y, et al. Chronic stress model simulated by salbutamol promotes tumorigenesis of gastric cancer cells through β2-AR/ERK/EMT pathway. J Cancer. 2022 Jan 1;13(2):401-412.
[2]. Hong YP, et al. Effects of Castanospermine on Inflammatory Response in a Rat Model of Experimental Severe Acute Pancreatitis. Arch Med Res. 2016 Aug;47(6):436-445.
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